highly cited
Our research ranks among the top 1% most cited works across several different fields

* corresponding author


Crean, E. E., Bilstein-Schloemer, M., Maekawa, T., Schulze-Lefert, P., Saur, I. M. L. 2023. A dominant-negative avirulence effector of the barley powdery mildew fungus provides mechanistic insight to barley MLA immune receptor activation. Journal of Experimental Botany, in press.

Cao, Y., F. Kümmel, E. Logemann, J. M. Gebauer, A. W. Lawson, D. Yu, M. Uthoff, B. Keller, J. Jirschitzka, U. Baumann, K. Tsuda, J. Chai*, and P. Schulze-Lefert*. 2023. Structural polymorphisms within a common powdery mildew effector scaffold as a driver of co-evolution with cereal immune receptors. Proceedings of the National Academy of Sciences of the United States of America. Proceedings of the National Academy of Sciences of the United States of America 120 (32). doi: 10.1073/pnas.2307604120. abstract

Getzke, F., M. A. Hassani, M. Cruesemann, M. Malisic, P. F. Zhang, Y. Ishigaki, N. Boehringer, A. J. Fernandez, L. Wang, J. Ordon, K. W. Ma, T. Thiergart, C. J. Harbort, H. Wesseler, S. Miyauchi, R. Garrido-Oter, K. Shirasu, T. F. Schaberle, S. Hacquard*, and P. Schulze-Lefert*. 2023. Cofunctioning of bacterial exometabolites drives root microbiota establishment. Proceedings of the National Academy of Sciences of the United States of America 120 (15). doi: 10.1073/pnas.2221508120. abstract 

Ordon, J., N. Kiel, D. Becker, C. Kretschmer, P. Schulze-Lefert, and J. Stuttmann. 2023. Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two. Plant Methods 19 (1). doi: 10.1186/s13007-023-01010-4. abstract


Acevedo-Garcia, J., K. Walden, F. Leissing, K. Baumgarten, K. Drwiega, M. Kwaaitaal, A. Reinstadler, M. Freh, X. Dong, G. V. James, L. C. Baus, M. Mascher, N. Stein, K. Schneeberger, N. Brocke-Ahmadinejad, M. Kollmar, P. Schulze-Lefert, and R. Panstruga. 2022. Barley Ror1 encodes a class XI myosin required for mlo-based broad-spectrum resistance to the fungal powdery mildew pathogen. Plant Journal 112 (1):84-103. doi: 10.1111/tpj.15930. abstract

Bourceret, A., R. Guan, K. Dorau, T. Mansfeldt, A. Omidbakhshfard, D. B. Medeiros, A. R. Fernie, J. Hofmann, U. Sonnewald, J. Mayer, N. Gerlach, M. Bucher, R. Garrido-Oter*, S. Spaepen*, P. Schulze-Lefert*, and Reconstruct Consortium. 2022. Maize Field Study Reveals Covaried Microbiota and Metabolic Changes in Roots over Plant Growth. Mbio 13 (2). doi: 10.1128/mbio.02584-21. abstract

Förderer, A., E. Li, A. W. Lawson, Y. N. Deng, Y. Sun, E. Logemann, X. X. Zhang, J. Wen, Z. F. Han, J. B. Chang, Y. H. Chen*, P. Schulze-Lefert*, and J. J. Chai*. 2022. A wheat resistosome defines common principles of immune receptor channels. Nature 610 (7932):532-+. doi: 10.1038/s41586-022-05231-w. abstract

Meyer, F., A. Fritz, Z. L. Deng, D. Koslicki, T. R. Lesker, A. Gurevich, G. Robertson, M. Alser, …P. Schulze-Lefert, … and A. C. McHardy. 2022. Critical Assessment of Metagenome Interpretation: the second round of challenges. Nature Methods 19 (4):429-+. doi: 10.1038/s41592-022-01431-4. abstract

Saur, I. M. L.*, A. W. Lawson, and P. Schulze-Lefert*. 2022. Buy one, get two. Nature Plants 8 (2):100-101. doi: 10.1038/s41477-022-01097-y. abstract

Yu, D. L., W. Song, E. Y. J. Tan, L. Liu, Y. Cao, J. Jirschitzka, E. R. Li, E. Logemann, C. R. Xu, S. J. Huang, A. L. Jia, X. Y. Chang, Z. F. Han, B. Wu*, P. Schulze-Lefert*, and J. J. Chai*. 2022. TIR domains of plant immune receptors are 2 ',3 '-cAMP/cGMP synthetases mediating cell death. Cell 185 (13):2370-+. doi: 10.1016/j.cell.2022.04.032. abstract

  • This work was featured by: Tian L, Li X. TIR domains as two-tiered enzymes to activate plant immunity. Cell. 2022 Jun 23;185(13):2208-2209. doi: 10.1016/j.cell.2022.05.025.


Bauer, S., D. L. Yu, A. W. Lawson, I. M. L. Saur, L. Frantzeskakis, B. Kracher, E. Logemann, J. J. Chai, T. Maekawa, and P. Schulze-Lefert*. 2021. The leucine-rich repeats in allelic barley MLA immune receptors define specificity towards sequence-unrelated powdery mildew avirulence effectors with a predicted common RNase-like fold. Plos Pathogens 17 (2). doi: 10.1371/journal.ppat.1009223. abstract

Durán, P., A. Reinstädler, A. L. Rajakrut, M. Hashimoto, R. Garrido-Oter*, P. Schulze-Lefert*, and R. Panstruga*. 2021. A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota. Environmental Microbiology 23 (10):6292-6308. doi: 10.1111/1462-2920.15768. abstract

Emonet, A., F. Zhou, J. Vacheron, C. M. Heiman, V. D. Tendon, K. W. Ma, P. Schulze-Lefert, C. Keel, and N. Geldner. 2021. Spatially Restricted Immune Responses Are Required for Maintaining Root Meristematic Activity upon Detection of Bacteria. Current Biology 31 (5). doi: 10.1016/j.cub.2020.12.048. abstract

Frerigmann, H., M. Piotrowski, R. Lemke, P. Bednarek, and P. Schulze-Lefert*. 2021. A Network of Phosphate Starvation and Immune-Related Signaling and Metabolic Pathways Controls the Interaction between Arabidopsis thaliana and the Beneficial Fungus Colletotrichum tofieldiae. Molecular Plant-Microbe Interactions 34 (5):560-570. doi: 10.1094/mpmi-08-20-0233-r. abstract

Kremer, J. M., R. Sohrabi, B. C. Paasch, D. Rhodes, C. Thireault, P. Schulze-Lefert, J. M. Tiedje, and S. Y. He. 2021. Peat-based gnotobiotic plant growth systems for Arabidopsis microbiome research. Nature Protocols 16 (5). doi: 10.1038/s41596-021-00504-6. abstract

Ma, K. W., Y. L. Niu, Y. Jia, J. Ordon, C. Copeland, A. Emonet, N. Geldner, R. Guan, S. C. Stolze, H. Nakagami, R. Garrido-Oter, and P. Schulze-Lefert*. 2021. Coordination of microbe-host homeostasis by crosstalk with plant innate immunity. Nature Plants 7 (6):814-+. doi: 10.1038/s41477-021-00920-2. abstract

Saur, I. M. L., R. Panstruga, and P. Schulze-Lefert*. 2021. NOD-like receptor-mediated plant immunity: from structure to cell death. Nature Reviews Immunology 21 (5):305-318. doi: 10.1038/s41577-020-00473-z. abstract

Schütz, V., K. Frindte, J. X. Cui, P. F. Zhang, S. Hacquard, P. Schulze-Lefert, C. Knief, M. Schulz, and P. Dormann. 2021. Differential Impact of Plant Secondary Metabolites on the Soil Microbiota. Frontiers in Microbiology 12. doi: 10.3389/fmicb.2021.666010. abstract

Winkelmuller, T. M., F. Entila, S. Anver, A. Piasecka, B. X. Song, E. Dahms, H. Sakakibara, X. C. Gan, K. Kulak, A. Sawikowska, P. Krajewski, M. Tsiantis, R. Garrido-Oter, K. Fukushima, P. Schulze-Lefert, S. Laurent, P. Bednarek, and K. Tsuda. 2021.  Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species. Plant Cell 33 (6):1863-1887. doi: 10.1093/plcell/koab073. abstract

Wippel, K., K. Tao, Y. L. Niu, R. Zgadzaj, N. Kiel, R. Guan, E. Dahms, P. F. Zhang, D. B. Jensen, E. Logemann, S. Radutoiu*, P. Schulze-Lefert*, and R. Garrido-Oter*. 2021. Host preference and invasiveness of commensal bacteria in the Lotus and Arabidopsis root microbiota. Nature Microbiology 6 (9):1150-+. doi: 10.1038/s41564-021-00941-9. abstract

Zhang, J. Y., Y. X. Liu, X. X. Guo, Y. Qin, R. Garrido-Oter*, P. Schulze-Lefert*, and Y. Bai*. 2021. High-throughput cultivation and identification of bacteria from the plant root microbiota. Nature Protocols 16 (2). doi: 10.1038/s41596-020-00444-7. abstract


Copeland, C., and P. Schulze-Lefert*. 2020. Leaf-derived bacterial communities adapt to the local environment. Proceedings of the National Academy of Sciences of the United States of America 117 (2):808-810. doi: 10.1073/pnas.1920431117. abstract

Harbort, C. J., Hashimoto, J., Inoue, H., Schulze-Lefert, P. (2020) A gnotobiotic growth assay for Arabidopsis root microbiota reconstitution under iron limitation. STAR Protocols 15;1(3):100226, doi: 10.1016/j.xpro.2020.100226. abstract

Harbort, C. J., M. Hashimoto, H. Inoue, Y. L. Niu, R. Guan, A. D. Rombola, S. Kopriva, Mjeee Voges, E. S. Sattely, R. Garrido-Oter*, and P. Schulze-Lefert*. 2020. Root-Secreted Coumarins and the Microbiota Interact to Improve Iron Nutrition in Arabidopsis. Cell Host & Microbe 28 (6):825-+. doi: 10.1016/j.chom.2020.09.006. abstract

Hematy, K., M. Lim, C. Cherk, M. Pislewska-Bednarek, C. Sanchez-Rodriguez, M. Stein, R. Fuchs, C. Klapprodt, V. Lipka, A. Molina, E. Grill, P. Schulze-Lefert, P. Bednarek, and S. Somerville. 2020. Moonlighting Function of Phytochelatin Synthase1 in Extracellular Defense against Fungal Pathogens (1)( OPEN ). Plant Physiology 182 (4):1920-1932. doi: 10.1104/pp.19.01393. abstract

Ma, S. C., D. Lapin, L. Liu, Y. Sun, W. Song, X. X. Zhang, E. Logemann, D. L. Yu, J. Wang, J. Jirschitzka, Z. F. Han, P. Schulze-Lefert*, J. E. Parker*, and J. J. Chai*. 2020. Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science 370 (6521):1184-+. doi: 10.1126/science.abe3069. abstract

Mahdi, L. K., M. H. Huang, X. X. Zhang, R. T. Nakano, L. B. Kopp, I. M. L. Saur, F. Jacob, V. Kovacova, D. Lapin, J. E. Parker, J. M. Murphy, K. Hofmann, P. Schulze-Lefert, J. J. Chai, and T. Maekawa. 2020. Discovery of a Family of Mixed Lineage Kinase Domain-like Proteins in Plants and Their Role in Innate Immune Signaling. Cell Host & Microbe 28 (6):813-+. doi: 10.1016/j.chom.2020.08.012. abstract

Nakano, R. T., N. Ishihama, Y. M. Wang, J. Takagi, T. Uemura, P. Schulze-Lefert, and H. Nakagami. 2020. Apoplastic Fluid Preparation from Arabidopsis thaliana Leaves Upon Interaction with a Nonadapted Powdery Mildew Pathogen. In PLANT PROTEOMICS, 3 EDITION: Methods and Protocols, edited by J. V. Jorrin-Novo, L. Valledor, M. A. Castillejo and M. D. Rey, 79-88. abstract

Thiergart, T., P. Duran, T. Ellis, N. Vannier, R. Garrido-Oter, E. Kemen, F. Roux, C. Alonso-Blanco, J. Agren*, P. Schulze-Lefert*, and S. Hacquard*. 2020. Root microbiota assembly and adaptive differentiation among European Arabidopsis populations. Nature Ecology & Evolution 4 (1):122-+. doi: 10.1038/s41559-019-1063-3. abstract


Berens, M. L., K. W. Wolinska, S. Spaepen, J. Ziegler, T. Nobori, A. Nair, V. Kruler, T. M. Winkelmuller, Y. M. Wang, A. Mine, D. Becker, R. Garrido-Oter, P. Schulze-Lefert*, and K. Tsuda*. 2019. Balancing trade-offs between biotic and abiotic stress responses through leaf age-dependent variation in stress hormone cross-talk. Proceedings of the National Academy of Sciences of the United States of America 116 (6):2364-2373. doi: 10.1073/pnas.1817233116. abstract

Maekawa, T., B. Kracher, I. M. L. Saur, M. Yoshikawa-Maekawa, R. Kellner, A. Pankin, M. von Korff, and P. Schulze-Lefert. 2019. Subfamily-Specific Specialization of RGH1/MLA Immune Receptors in Wild Barley. Molecular Plant-Microbe Interactions 32 (1):107-119. doi: 10.1094/mpmi-07-18-0186-fi. abstract

Saur, I. M. L., S. Bauer, B. Kracher, X. L. Lu, L. Franzeskakis, M. C. Muller, B. Sabelleck, F. Kummel, R. Panstruga, T. Maekawa, and P. Schulze-Lefert*. 2019. Multiple pairs of allelic MLA immune receptor-powdery mildew AVR(A) effectors argue for a direct recognition mechanism. Elife 8. doi: 10.7554/eLife.44471. abstract

Saur, I. M. L.*, S. Bauer, X. L. Lu, and P. Schulze-Lefert*. 2019. A cell death assay in barley and wheat protoplasts for identification and validation of matching pathogen AVR effector and plant NLR immune receptors. Plant Methods 15 (1). doi: 10.1186/s13007-019-0502-0. abstract

Thiergart, T., R. Zgadzaj, Z. Bozsoki, R. Garrido-Oter, S. Radutoiu*, and P. Schulze-Lefert*. 2019. Lotus japonicus Symbiosis Genes Impact Microbial Interactions between Symbionts and Multikingdom Commensal Communities. Mbio 10 (5). doi: 10.1128/mBio.01833-19. abstract 

Uemura, T., R. T. Nakano, J. Takagi, Y. M. Wang, K. Kramer, I. Finkemeier, H. Nakagami, K. Tsuda, T. Ueda, P. Schulze-Lefert, and A. Nakano. 2019. A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis. Plant Physiology 179 (2):519-532. doi: 10.1104/pp.18.01228. abstract

Voges, Mjeee, Y. Bai, P. Schulze-Lefert, and E. S. Sattely. 2019. Plant-derived coumarins shape the composition of an Arabidopsis synthetic root microbiome. Proceedings of the National Academy of Sciences of the United States of America 116 (25):12558-12565. doi: 10.1073/pnas.1820691116. abstract

Wippel, K., Schulze-Lefert, P.*, Garrido-Oter, R.*: Rhizobien in der Pflanzenmikrobiota: Evolution der Wurzelknöllchensymbiose und Funktionen der Mikrobiota für den Pflanzenwirt. Biologie in unserer Zeit 6 (49) , 426-434 (2019). abstract


Durán, P., T. Thiergart, R. Garrido-Oter, M. Agler, E. Kemen, P. Schulze-Lefert*, and S. Hacquard*. 2018. Microbial Interkingdom Interactions in Roots Promote Arabidopsis Survival. Cell 175 (4):973-+. doi: 10.1016/j.cell.2018.10.020. abstract

Frantzeskakis, L., B. Kracher, S. Kusch, M. Yoshikawa-Maekawa, S. Bauer, C. Pedersen, P. D. Spanu, T. Maekawa, P. Schulze-Lefert*, and R. Panstruga*. 2018. Signatures of host specialization and a recent transposable element burst in the dynamic one-speed genome of the fungal barley powdery mildew pathogen. Bmc Genomics 19. doi: 10.1186/s12864-018-4750-6. abstract

Garrido-Oter, R., R. T. Nakano, N. Dombrowski, K. W. Ma, A. C. McHardy, P. Schulze-Lefert*, and Team AgBiome. 2018. Modular Traits of the Rhizobiales Root Microbiota and Their Evolutionary Relationship with Symbiotic Rhizobia. Cell Host & Microbe 24 (1):155-+. doi: 10.1016/j.chom.2018.06.006. abstract

  • This work was featured in: Willige, B.C., Chory, J, Burger M. Next generation of Plant-Associated Bacterial Genome Data. Cell Host & Microbe 24: 10-11 (2018). DOI: 10.1016/j.chom.2018.06.009

Jacob, F., B. Kracher, A. Mine, C. Seyfferth, S. Blanvillain-Baufume, J. E. Parker, K. Tsuda, P. Schulze-Lefert*, and T. Maekawa*. 2018. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytologist 217 (4):1667-1680. doi: 10.1111/nph.14943. abstract

Pislewska-Bednarek, M., R. T. Nakano, K. Hiruma, M. Pastorczyk, A. Sanchez-Vallet, S. Singkaravanit-Ogawa, D. Ciesiolka, Y. Takano, A. Molina, P. Schulze-Lefert, and P. Bednarek. 2018. Glutathione Transferase U13 Functions in Pathogen-Triggered Glucosinolate Metabolism. Plant Physiology 176 (1):538-551. doi: 10.1104/pp.17.01455. abstract

Robbins, C., T. Thiergart, S. Hacquard, R. Garrido-Oter, W. Gans, E. Peiter, P. Schulze-Lefert*, and S. Spaepen*. 2018. Root-Associated Bacterial and Fungal Community Profiles of Arabidopsis thaliana Are Robust Across Contrasting Soil P Levels. Phytobiomes Journal 2 (1):24-34. doi: 10.1094/pbiomes-09-17-0042-r. abstract

Sopeña-Torres, S., L. Jorda, C. Sanchez-Rodriguez, E. Miedes, V. Escudero, S. Swami, G. Lopez, M. Pislewska-Bednarek, I. Lassowskat, J. Lee, Y. N. Gu, S. Haigis, D. Alexander, S. Pattathil, A. Munoz-Barrios, P. Bednarek, S. Somerville, P. Schulze-Lefert, M. G. Hahn, D. Scheel, and A. Molina. 2018. YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance. New Phytologist 218 (2):661-680. doi: 10.1111/nph.15007. abstract

Wibowo, A., C. Becker, J. Durr, J. Price, S. Spaepen, S. Hilton, H. Putra, R. Papareddy, Q. Saintain, S. Harvey, G. D. Bending, P. Schulze-Lefert, D. Weigel, and J. Gutierrez-Marcos. 2018. Partial maintenance of organ-specific epigenetic marks during plant asexual reproduction leads to heritable phenotypic variation. Proceedings of the National Academy of Sciences of the United States of America 115 (39):E9145-E9152. doi: 10.1073/pnas.1805371115. abstract


Dombrowski, N., K. Schlaeppi, M. T. Agler, S. Hacquard, E. Kemen, R. Garrido-Oter, J. Wunder, G. Coupland, and P. Schulze-Lefert*. 2017. Root microbiota dynamics of perennial Arabis alpina are dependent on soil residence time but independent of flowering time. Isme Journal 11 (1):43-55. doi: 10.1038/ismej.2016.109. abstract

Fukunaga, S., M. Sogame, M. Hata, S. Singkaravanit-Ogawa, M. Pislewska-Bednarek, M. Onozawa-Komori, T. Nishiuchi, K. Hiruma, H. Saitoh, R. Terauchi, S. Kitakura, Y. Inoue, P. Bednarek, P. Schulze-Lefert, and Y. Takano. 2017. Dysfunction of Arabidopsis MACPF domain protein activates programmed cell death via tryptophan metabolism in MAMP-triggered immunity. Plant Journal 89 (2):381-393. doi: 10.1111/tpj.13391. abstract

Hacquard, S., S. Spaepen, R. Garrido-Oter, and P. Schulze-Lefert*. 2017. Interplay Between Innate Immunity and the Plant Microbiota. In Annual Review of Phytopathology, Vol 55, edited by J. E. Leach and S. E. Lindow, 565-589.

Maekawa, T., and P. Schulze-Lefert. 2017. Caught in the jump. Science 357 (6346):31-32. doi: 10.1126/science.aan8287. abstract

Nakano, R. T., M. Pislewska-Bednarek, K. Yamada, P. P. Edger, M. Miyahara, M. Kondo, C. Bottcher, M. Mori, M. Nishimura, P. Schulze-Lefert*, I. Hara-Nishimura*, and P. Bednarek*. 2017. PYK10 myrosinase reveals a functional coordination between endoplasmic reticulum bodies and glucosinolates in Arabidopsis thaliana. Plant Journal 89 (2):204-220. doi: 10.1111/tpj.13377. abstract

Sczyrba, A., P. Hofmann, P. Belmann, D. Koslicki, S. Janssen, J. Droge, I. Gregor, S. Majda, … P. Schulze-Lefert, … and A. C. McHardy. 2017. Critical Assessment of Metagenome Interpretation-a benchmark of metagenomics software. Nature Methods 14 (11):1063-+. doi: 10.1038/nmeth.4458. abstract


Hacquard, S., B. Kracher, K. Hiruma, P. C. Munch, R. Garrido-Oter, M. R. Thon, A. Weimann, U. Damm, J. F. Dallery, M. Hainaut, B. Henrissat, O. Lespinet, S. Sacristan, E. V. L. van Themaat, E. Kemen, A. C. McHardy, P. Schulze-Lefert*, and R. J. O'Connell*. 2016. Survival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi. Nature Communications 7:11362. doi: 10.1038/ncomms11362. absctract

Hiruma, K., N. Gerlach, S. Sacristan, R. T. Nakano, S. Hacquard, B. Kracher, U. Neumann, D. Ramirez, M. Bucher, R. J. O'Connell*, and P. Schulze-Lefert*. 2016. Root Endophyte Colletotrichum tofieldiae Confers Plant Fitness Benefits that Are Phosphate Status Dependent. Cell 165 (2):464-474. doi: 10.1016/j.cell.2016.02.028. abstract

Lu, X. L., B. Kracher, I. M. L. Saur, S. Bauer, S. R. Ellwood, R. Wise, T. Yaeno, T. Maekawa, and P. Schulze-Lefert*. 2016. Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen. Proceedings of the National Academy of Sciences of the United States of America 113 (42):E6486-E6495. doi: 10.1073/pnas.1612947113. abstract

Zgadzaj, R., R. Garrido-Oter, D. B. Jensen, A. Koprivova, P. Schulze-Lefert*, and S. Radutoiu*. 2016. Root nodule symbiosis in Lotus japonicus drives the establishment of distinctive rhizosphere, root, and nodule bacterial communities. Proceedings of the National Academy of Sciences of the United States of America 113 (49):E7996-E8005. doi: 10.1073/pnas.1616564113. abstract


Bai, Y., D. B. Muller, G. Srinivas, R. Garrido-Oter, E. Potthoff, M. Rott, N. Dombrowski, P. C. Munch, S. Spaepen, M. Remus-Emsermann, B. Huttel, A. C. McHardy, J. A. Vorholt*, and P. Schulze-Lefert*. 2015. Functional overlap of the Arabidopsis leaf and root microbiota. Nature 528 (7582):364-+. doi: 10.1038/nature16192. abstract

  • This work was featured in: Nature (2015), doi:10.1038/nature16319, by Gwyn A. Beattie: Microbiomes: Curating communities from plants

Bulgarelli, D., R. Garrido-Oter, P. C. Munch, A. Weiman, J. Droge, Y. Pan, A. C. McHardy*, and P. Schulze-Lefert*. 2015. Structure and Function of the Bacterial Root Microbiota in Wild and Domesticated Barley. Cell Host & Microbe 17 (3):392-403. doi: 10.1016/j.chom.2015.01.011. abstract

Hacquard, S., R. Garrido-Oter, A. Gonzalez, S. Spaepen, G. Ackermann, S. Lebeis, A. C. McHardy*, J. L. Dangl*, R. Knight*, R. Ley*, and P. Schulze-Lefert*. 2015. Microbiota and Host Nutrition across Plant and Animal Kingdoms. Cell Host & Microbe 17 (5):603-616. doi: 10.1016/j.chom.2015.04.009. abstract

Lu, X. L., J. Dittgen, M. Pislewska-Bednarek, A. Molina, B. Schneider, A. Svatos, J. Doubsky, K. Schneeberger, D. Weigel, P. Bednarek*, and P. Schulze-Lefert*. 2015. Mutant Allele-Specific Uncoupling of PENETRATION3 Functions Reveals Engagement of the ATP-Binding Cassette Transporter in Distinct Tryptophan Metabolic Pathways. Plant Physiology 168 (3):814-+. doi: 10.1104/pp.15.00182. abstract

Zamioudis, C., J. Korteland, J. A. Van Pelt, M. van Hamersveld, N. Dombrowski, Y. Bai, J. Hanson, M. C. Van Verk, H. Q. Ling, P. Schulze-Lefert, and C. M. J. Pieterse. 2015. Rhizobacterial volatiles and photosynthesis-related signals coordinate MYB72 expression in Arabidopsis roots during onset of induced systemic resistance and iron-deficiency responses. Plant Journal 84 (2):309-322. doi: 10.1111/tpj.12995. abstract


Dörmann, P., H. Kim, T. Ott, P. Schulze-Lefert, M. Trujillo, V. Wewer, and R. Huckelhoven. 2014. Cell-autonomous defense, re-organization and trafficking of membranes in plant-microbe interactions. New Phytologist 204 (4):815-822. doi: 10.1111/nph.12978. abstract

Guttman, D. S., A. C. McHardy, and P. Schulze-Lefert*. 2014. Microbial genome-enabled insights into plant-microorganism interactions. Nature Reviews Genetics 15 (12):797-813. doi: 10.1038/nrg3748. abstract

Ichikawa, M., T. Hirano, K. Enami, T. Fuselier, N. Kato, C. Kwon, B. Voigt, P. Schulze-Lefert, F. Baluska, and M. H. Sato. 2014. Syntaxin of Plant Proteins SYP123 and SYP132 Mediate Root Hair Tip Growth in Arabidopsis thaliana. Plant and Cell Physiology 55 (4):790-800. doi: 10.1093/pcp/pcu048. abstract

Kim, H., R. O'Connell, M. Maekawa-Yoshikawa, T. Uemura, U. Neumann, and P. Schulze-Lefert*. 2014. The powdery mildew resistance protein RPW8.2 is carried on VAMP721/722 vesicles to the extrahaustorial membrane of haustorial complexes. Plant Journal 79 (5):835-847. doi: 10.1111/tpj.12591. abstract

Schlaeppi, K., N. Dombrowski, R. G. Oter, E. V. L. van Themaat, and P. Schulze-Lefert*. 2014. Quantitative divergence of the bacterial root microbiota in Arabidopsis thaliana relatives. Proceedings of the National Academy of Sciences of the United States of America 111 (2):585-592. doi: 10.1073/pnas.1321597111. abstract

Wessling, R., P. Epple, S. Altmann, Y. J. He, L. Yang, S. R. Henz, N. McDonald, K. Wiley, K. C. Bader, C. Glasser, M. S. Mukhtar, S. Haigis, L. Ghamsari, A. E. Stephens, J. R. Ecker, M. Vidal, J. D. G. Jones, K. F. X. Mayer, E. V. van Themaat, D. Weigel, P. Schulze-Lefert, J. L. Dangl, R. Panstruga, and P. Braun. 2014. Convergent Targeting of a Common Host Protein-Network by Pathogen Effectors from Three Kingdoms of Life. Cell Host & Microbe 16 (3):364-375. doi: 10.1016/j.chom.2014.08.004. abstract


Acevedo-Garcia, J., N. C. Collins, N. Ahmadinejad, L. Ma, A. Houben, P. Bednarek, M. Benjdia, A. Freialdenhoven, J. Altmuller, P. Nurnberg, R. Reinhardt, P. Schulze-Lefert, and R. Panstruga. 2013. Fine mapping and chromosome walking towards the Ror1 locus in barley (Hordeum vulgare L.). Theoretical and Applied Genetics 126 (12):2969-2982. doi: 10.1007/s00122-013-2186-6. abstract

Bulgarelli, D., K. Schlaeppi, S. Spaepen, E. V. L. van Themaat, and P. Schulze-Lefert*. 2013. Structure and Functions of the Bacterial Microbiota of Plants. In Annual Review of Plant Biology, Vol 64, edited by S. S. Merchant, 807-838. abstract

Chang, C., D. S. Yu, J. Jiao, S. J. Jing, P. Schulze-Lefert, and Q. H. Shen. 2013. Barley MLA Immune Receptors Directly Interfere with Antagonistically Acting Transcription Factors to Initiate Disease Resistance Signaling. Plant Cell 25 (3):1158-1173. doi: 10.1105/tpc.113.109942. abstract

Hacquard, S., B. Kracher, T. Maekawa, S. Vernaldi, P. Schulze-Lefert*, and E. V. L. van Themaat*. 2013. Mosaic genome structure of the barley powdery mildew pathogen and conservation of transcriptional programs in divergent hosts. Proceedings of the National Academy of Sciences of the United States of America 110 (24):E2219-E2228. doi: 10.1073/pnas.1306807110. abstract

Kopischke, M., L. Westphal, K. Schneeberger, R. Clark, S. Ossowski, V. Wewer, R. Fuchs, J. Landtag, G. Hause, P. Dormann, V. Lipka, D. Weigel, P. Schulze-Lefert, D. Scheel, and S. Rosahl. 2013. Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans. Plant Journal 73 (3):456-468. doi: 10.1111/tpj.12046. abstract

Poraty-Gavra, L., P. Zimmermann, S. Haigis, P. Bednarek, O. Hazak, O. R. Stelmakh, E. Sadot, P. Schulze-Lefert, W. Gruissem, and S. Yalovsky. 2013. The Arabidopsis Rho of Plants GTPase AtROP6 Functions in Developmental and Pathogen Response Pathways. Plant Physiology 161 (3):1172-1188. doi: 10.1104/pp.112.213165. abstract

Wicker, T., S. Oberhaensli, F. Parlange, J. P. Buchmann, M. Shatalina, S. Roffler, R. Ben-David, J. Dolezel, H. Simkova, P. Schulze-Lefert, P. D. Spanu, R. Bruggmann, J. Amselem, H. Quesneville, E. V. L. van Themaat, T. Paape, K. K. Shimizu, and B. Keller. 2013. The wheat powdery mildew genome shows the unique evolution of an obligate biotroph. Nature Genetics 45 (9):1092-+. doi: 10.1038/ng.2704. abstract

Yun, H. S., M. Kwaaitaal, N. Kato, C. Yi, S. Park, M. H. Sato, P. Schulze-Lefert*, and C. Kwon*. 2013. Requirement of vesicle-associated membrane protein 721 and 722 for sustained growth during immune responses in Arabidopsis. Molecules and Cells 35 (6):481-488. doi: 10.1007/s10059-013-2130-2. abtract


Bai, S. W., J. Liu, C. Chang, L. Zhang, T. Maekawa, Q. Y. Wang, W. K. Xiao, Y. L. Liu, J. J. Chai, F. L. W. Takken, P. Schulze-Lefert, and Q. H. Shen. 2012. Structure-Function Analysis of Barley NLR Immune Receptor MLA10 Reveals Its Cell Compartment Specific Activity in Cell Death and Disease Resistance. Plos Pathogens 8 (6). doi: 10.1371/journal.ppat.1002752. abstract

Bulgarelli, D., M. Rott, K. Schlaeppi, E. V. L. van Themaat, N. Ahmadinejad, F. Assenza, P. Rauf, B. Huettel, R. Reinhardt, E. Schmelzer, J. Peplies, F. O. Gloeckner, R. Amann, T. Eickhorst, and P. Schulze-Lefert*. 2012. Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiota. Nature 488 (7409):91-95. doi: 10.1038/nature11336. abstract

Delgado-Cerezo, M., C. Sanchez-Rodriguez, V. Escudero, E. Miedes, P. V. Fernandez, L. Jorda, C. Hernandez-Blanco, A. Sanchez-Vallet, P. Bednarek, P. Schulze-Lefert, S. Somerville, J. M. Estevez, S. Persson, and A. Molina. 2012. Arabidopsis Heterotrimeric G-protein Regulates Cell Wall Defense and Resistance to Necrotrophic Fungi. Molecular Plant 5 (1):98-114. doi: 10.1093/mp/ssr082. abstract

Lebeis, S. L., M. Rott, J. L. Dangl, and P. Schulze-Lefert*. 2012. Culturing a plant microbiome community at the cross-Rhodes. New Phytologist 196 (2):341-344. doi: 10.1111/j.1469-8137.2012.04336.x. abstract

Maekawa, T.*, B. Kracher, S. Vernaldi, E. V. L. van Themaat, and P. Schulze-Lefert*. 2012. Conservation of NLR-triggered immunity across plant lineages. Proceedings of the National Academy of Sciences of the United States of America 109 (49):20119-20123. doi: 10.1073/pnas.1218059109. abstract

O'Connell, R. J., M. R. Thon, S. Hacquard, S. G. Amyotte, J. Kleemann, M. F. Torres, U. Damm, E. A. Buiate, … P. Schulze-Lefert, … and L. J. Vaillancourt. 2012. Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses. Nature Genetics 44 (9):1060-+. doi: 10.1038/ng.2372.Serrano, M., K. Kanehara, M. Torres, K. Yamada, N. Tintor, E. Kombrink, P. Schulze-Lefert, and Y. Saijo. 2012. Repression of Sucrose/Ultraviolet B Light-Induced Flavonoid Accumulation in Microbe-Associated Molecular Pattern-Triggered Immunity in Arabidopsis. Plant Physiology 158 (1):408-422. doi: 10.1104/pp.111.183459. abstract

Uemura, T., H. Kim, C. Saito, K. Ebine, T. Ueda, P. Schulze-Lefert, and A. Nakano. 2012. Qa-SNAREs localized to the trans-Golgi network regulate multiple transport pathways and extracellular disease resistance in plants. Proceedings of the National Academy of Sciences of the United States of America 109 (5):1784-1789. doi: 10.1073/pnas.1115146109. abstract


Bednarek, P*., M. Pislewska-Bednarek, E. V. L. van Themaat, R. K. Maddula, A. Svatos, and P. Schulze-Lefert*. 2011. Conservation and clade-specific diversification of pathogen-inducible tryptophan and indole glucosinolate metabolism in Arabidopsis thaliana relatives. New Phytologist 192 (3):713-726. doi: 10.1111/j.1469-8137.2011.03824.x. abstract

  • New Phytologist (2011) 192: 566-569 by Nicole K. Clay: Chemical diversity on display in the plant innate immune systems of closely-related species

Hiruma, K., T. Nishiuchi, T. Kato, P. Bednarek, T. Okuno, P. Schulze-Lefert, and Y. Takano. 2011. Arabidopsis ENHANCED DISEASE RESISTANCE 1 is required for pathogen-induced expression of plant defensins in nonhost resistance, and acts through interference of MYC2-mediated repressor function. Plant Journal 67 (6):980-992. doi: 10.1111/j.1365-313X.2011.04651.x. abstract

Maekawa, T., W. Cheng, L. N. Spiridon, A. Toller, E. Lukasik, Y. Saijo, P. Y. Liu, Q. H. Shen, M. A. Micluta, I. E. Somssich, F. L. W. Takken, A. J. Petrescu, J. J. Chai*, and P. Schulze-Lefert*. 2011. Coiled-Coil Domain-Dependent Homodimerization of Intracellular Barley Immune Receptors Defines a Minimal Functional Module for Triggering Cell Death. Cell Host & Microbe 9 (3):187-199. doi: 10.1016/j.chom.2011.02.008.

Maekawa, T., T. A. Kufer, and P. Schulze-Lefert*. 2011. NLR functions in plant and animal immune systems: so far and yet so close. Nature Immunology 12 (9):818-826. doi: 10.1038/ni.2083. abstract

Schulze-Lefert, P*., and R. Panstruga*. 2011. A molecular evolutionary concept connecting nonhost resistance, pathogen host range, and pathogen speciation. Trends in Plant Science 16 (3):117-125. doi: 10.1016/j.tplants.2011.01.001. abstract


Bednarek, P.*, C. Kwon, and P. Schulze-Lefert*. 2010. Not a peripheral issue: secretion in plant-microbe interactions. Current Opinion in Plant Biology 13 (4):378-387. doi: 10.1016/j.pbi.2010.05.002. abstract

Bulgarelli, D., C. Biselli, N. C. Collins, G. Consonni, A. M. Stanca, P. Schulze-Lefert, and G. Vale*. 2010. The CC-NB-LRR-Type Rdg2a Resistance Gene Confers Immunity to the Seed-Borne Barley Leaf Stripe Pathogen in the Absence of Hypersensitive Cell Death. Plos One 5 (9). doi: 10.1371/journal.pone.0012599. abstract

Christensen, A., K. Svensson, L. Thelin, W. J. Zhang, N. Tintor, D. Prins, N. Funke, M. Michalak, P. Schulze-Lefert, Y. Saijo, M. Sommarin, S. Widell, and S. Persson. 2010. Higher Plant Calreticulins Have Acquired Specialized Functions in Arabidopsis. Plos One 5 (6). doi: 10.1371/journal.pone.0011342. abstract

Hiruma, K., M. Onozawa-Komori, F. Takahashi, M. Asakura, P. Bednarek, T. Okuno, P. Schulze-Lefert, and Y. Takano. 2010. Entry Mode-Dependent Function of an Indole Glucosinolate Pathway in Arabidopsis for Nonhost Resistance against Anthracnose Pathogens. Plant Cell 22 (7):2429-2443. doi: 10.1105/tpc.110.074344. abstract

Humphry, M., P. Bednarek, B. Kemmerling, S. Koh, M. Stein, U. Gobel, K. Stuber, M. Pislewska-Bednarek, A. Loraine, P. Schulze-Lefert, S. Somerville, and R. Panstruga*. 2010. A regulon conserved in monocot and dicot plants defines a functional module in antifungal plant immunity. Proceedings of the National Academy of Sciences of the United States of America 107 (50):21896-21901. doi: 10.1073/pnas.1003619107. abstract

Salomon, S., D. Grunewald, K. Stuber, S. Schaaf, D. MacLean, P. Schulze-Lefert*, and S. Robatzek*. 2010. High-Throughput Confocal Imaging of Intact Live Tissue Enables Quantification of Membrane Trafficking in Arabidopsis. Plant Physiology 154 (3):1096-1104. doi: 10.1104/pp.110.160325. abstract

Sanchez-Vallet, A., B. Ramos, P. Bednarek, G. Lopez, M. Pislewska-Bednarek, P. Schulze-Lefert, and A. Molina. 2010. Tryptophan-derived secondary metabolites in Arabidopsis thaliana confer non-host resistance to necrotrophic Plectosphaerella cucumerina fungi. Plant Journal 63 (1):115-127. doi: 10.1111/j.1365-313X.2010.04224.x. abstract

Schulze-Lefert, P.* 2010. 99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Innate immune responses in plants. Clinical and Experimental Immunology 160 (1):62-69. doi: 10.1111/j.1365-2249.2010.04134.x.  abstract

Seeholzer, S., T. Tsuchimatsu, T. Jordan, S. Bieri, S. Pajonk, W. X. Yang, A. Jahoor, K. K. Shimizu, B. Keller*, and P. Schulze-Lefert*. 2010. Diversity at the Mla Powdery Mildew Resistance Locus from Cultivated Barley Reveals Sites of Positive Selection. Molecular Plant-Microbe Interactions 23 (4):497-509. doi: 10.1094/mpmi-23-4-0497. abstract

Serrano, M., D. A. Hubert, J. L. Dangl, P. Schulze-Lefert, and E. Kombrink. 2010. A chemical screen for suppressors of the avrRpm1-RPM1-dependent hypersensitive cell death response in Arabidopsis thaliana. Planta 231 (5):1013-1023. doi: 10.1007/s00425-010-1105-1. abstract

Spanu, P. D., J. C. Abbott, J. Amselem, T. A. Burgis, D. M. Soanes, K. Stuber, E. V. L. van Themaat, J. K. M. Brown, … P. Schulze-Lefert, … and R. Panstruga. 2010. Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism. Science 330 (6010):1543-1546. doi: 10.1126/science.1194573. abstract


Bednarek, P.*, M. Pislewska-Bednarek, A. Svatos, B. Schneider, J. Doubsky, M. Mansurova, M. Humphry, C. Consonni, R. Panstruga, A. Sanchez-Vallet, A. Molina, and P. Schulze-Lefert*. 2009. A Glucosinolate Metabolism Pathway in Living Plant Cells Mediates Broad-Spectrum Antifungal Defense. Science 323 (5910):101-106. doi: 10.1126/science.1163732. abstract

  • This work was featured in: ACS Chem. Biol. 4 (2), 80-84. DOI: 10.1021/cb9000266, pp 82 - 83.

Bednarek, Pawel and P. Schulze-Lefert: Role of Plant Secondary Metabolites at the host-pathogen Interface (2009). In: Annual Plant Reviews, 34, Chapter 8, 220 - 260

Bednarek, P., and P. Schulze-Lefert. 2009 .Role of Plant Secondary Metabolites at the Host–Pathogen Interface. In Molecular Aspects of Plant Disease Resistance, edited by J. Parker, 220-260.

Bisseling, T.*, J. L. Dangl*, and P. Schulze-Lefert*. 2009. Next-Generation Communication. Science 324 (5928):691-691. doi: 10.1126/science.1174404. abstract

Lu, X., N. Tintor, T. Mentzel, E. Kombrink, T. Boller, S. Robatzek, P. Schulze-Lefert*, and Y. Saijo*. 2009. Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis endoplasmic reticulum glucosidase II allele. Proceedings of the National Academy of Sciences of the United States of America 106 (52):22522-22527. doi: 10.1073/pnas.0907711106. abstract

Meyer, D., S. Pajonk, C. Micali, R. O'Connell*, and P. Schulze-Lefert*. 2009. Extracellular transport and integration of plant secretory proteins into pathogen-induced cell wall compartments. Plant Journal 57 (6):986-999. doi: 10.1111/j.1365-313X.2008.03743.x. abstract

Panstruga, R.*, J. E. Parker, and P. Schulze-Lefert. 2009. SnapShot: Plant Immune Response Pathways. Cell 136 (5):978-U6. doi: 10.1016/j.cell.2009.02.020. abstract

Saijo, Y.*, N. Tintor, X. L. Lu, P. Rauf, K. Pajerowska-Mukhtar, H. Haweker, X. N. Dong, S. Robatzek, and P. Schulze-Lefert*. 2009. Receptor quality control in the endoplasmic reticulum for plant innate immunity. Embo Journal 28 (21):3439-3449. doi: 10.1038/emboj.2009.263. abstract


Kwon, C., P. Bednarek, and P. Schulze-Lefert*. 2008. Secretory pathways in plant immune responses. Plant Physiology 147 (4):1575-1583. doi: 10.1104/pp.108.121566. abstract

Kwon, C., C. Neu, S. Pajonk, H. S. Yun, U. Lipka, M. Humphry, S. Bau, M. Straus, M. Kwaaitaal, H. Rampelt, F. El Kasmi, G. Jurgens, J. Parker, R. Panstruga, V. Lipka*, and P. Schulze-Lefert*. 2008. Co-option of a default secretory pathway for plant immune responses. Nature 451 (7180):835-U10. doi: 10.1038/nature06545. abstract

Kwon, C., R. Panstruga, and P. Schulze-Lefert*. 2008. Les liaisons dangereuses: immunological synapse formation in animals and plants. Trends in Immunology 29 (4):159-166. doi: 10.1016/ abstract

Pajonk, S., C. Kwon, N. Clemens, R. Panstruga, and P. Schulze-Lefert*. 2008. Activity determinants and functional specialization of Arabidopsis PEN1 syntaxin in innate immunity. Journal of Biological Chemistry 283 (40):26974-26984. doi:10.1074/jbc.M805236200. abstract

Saijo, Y., and P. Schulze-Lefert*. 2008. Manipulation of the eukaryotic transcriptional machinery by bacterial pathogens. Cell Host & Microbe 4 (2):96-99. doi: 10.1016/j.chom.2008.07.001. abstract

Toller, A., L. Brownfield, C. Neu, D. Twell, and P. Schulze-Lefert*. 2008. Dual function of Arabidopsis glucan synthase-like genes GSL8 and GSL10 in male gametophyte development and plant growth. Plant Journal 54 (5):911-923. doi: 10.1111/j.1365-313X.2008.03462.x. abstract

Yun, H.S., Panstruga, R., Schulze-Lefert, P., and Kwon, C. (2008) Ready to fire: Secretion in Plant Immunity. Plant Signaling and Behavior, 3: 505-508. abstract


Collins, N. C., R. E. Niks, and P. Schulze-Lefert. 2007. Resistance to cereal rusts at the plant cell wall - what can we learn from other host-pathogen systems? Australian Journal of Agricultural Research 58 (6):476-489. doi: 10.1071/ar06065. abstract

Miklis, M., C. Consonni, R. A. Bhat, V. Lipka, P. Schulze-Lefert, and R. Panstruga*. 2007. Barley MLO modulates actin-dependent and actin-independent antifungal defense pathways at the cell periphery. Plant Physiology 144 (2):1132-1143. doi: 10.1104/pp.107.098897. abstract

Serrano, M., S. Robatzek, M. Torres, E. Kombrink, I. E. Somssich, M. Robinson, and P. Schulze-Lefert*. 2007. Chemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals. Journal of Biological Chemistry 282 (9):6803-6811. doi: 10.1074/jbc.M608792200. abstract

Shen, Q. H., Y. Saijo, S. Mauch, C. Biskup, S. Bieri, B. Keller, H. Seki, B. Ulker, I. E. Somssich, and P. Schulze-Lefert*. 2007. Nuclear activity of MLA immune receptors links isolate-specific and basal disease-resistance responses. Science 315 (5815):1098-1103. doi: 10.1126/science.1136372. abstract

This work was featured in:

Shen, Q. H., and P. Schulze-Lefert*. 2007. Rumble in the nuclear jungle: compartmentalization, trafficking, and nuclear action of plant immune receptors. Embo Journal 26 (20):4293-4301. doi: 10.1038/sj.emboj.7601854. abstract


Batchu, A. K., D. Zimmermann, P. Schulze-Lefert, and T. Koprek. 2006. Correlation between hordatine accumulation, environmental factors and genetic diversity in wild barley (Hordeum spontaneum C. Koch) accessions from the Near East Fertile Crescent. Genetica 127 (1-3):87-99. doi: 10.1007/s10709-005-2484-2. abstract

Chen, Z. Y., H. A. Hartmann, M. J. Wu, E. J. Friedman, J. G. Chen, M. Pulley, P. Schulze-Lefert, R. Panstruga, and A. M. Jones. 2006. Expression analysis of the AtMLO gene family encoding plant-specific seven-transmembrane domain proteins. Plant Molecular Biology 60 (4):583-597. doi: 10.1007/s11103-005-5082-x. abstract

Consonni, C., M. E. Humphry, H. A. Hartmann, M. Livaja, J. Durner, L. Westphal, J. Vogel, V. Lipka, B. Kemmerling, P. Schulze-Lefert, S. C. Somerville, and R. Panstruga. 2006. Conserved requirement for a plant host cell protein in powdery mildew pathogenesis. Nature Genetics 38 (6):716-720. doi: 10.1038/ng1806. abstract

Schulze-Lefert, P*., and S. Robatzek. 2006. Plant pathogens trick guard cells into opening the gates. Cell 126 (5):831-834. doi: 10.1016/j.cell.2006.08.020. abstract

Shimada, C., V. Lipka, R. O'Connel, T. Okuno, P. Schulze-Lefert, and Y. Takano. 2006. Nonhost resistance in Arabidopsis-colletotrichum interactions acts at the cell periphery and requires actin filament function. Molecular Plant-Microbe Interactions 19 (3):270-279. doi: 10.1094/mpmi-19-0270. abstract

Stein, M., J. Dittgen, C. Sanchez-Rodriguez, B. H. Hou, A. Molina, P. Schulze-Lefert, V. Lipka, and S. Somerville. 2006. Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration. Plant Cell 18 (3):731-746. doi: 10.1105/tpc.105.038372. abstract

  • This work was featured in: The Plant Cell 18: 523-528, 2006, Ellis J.: Insights into nonhost disease resistance: Can they assist disease control in agriculture?

Swarbrick, P. J., P. Schulze-Lefert, and J. D. Scholes. 2006. Metabolic consequences of susceptibility and resistance (race-specific and broad-spectrum) in barley leaves challenged with powdery mildew. Plant Cell and Environment 29 (6):1061-1076. doi: 10.1111/j.1365-3040.2005.01472.x. abstract

Zhao, T., M. Palotta, P. Langridge, M. Prasad, A. Graner, P. Schulze-Lefert*, and T. Koprek*. 2006. Mapped Ds/T-DNA launch pads for functional genomics in barley. Plant Journal 47 (5):811-826. doi: 10.1111/j.1365-313X.2006.02831.x. abstract


Bhat, R. A., M. Miklis, E. Schmelzer, P. Schulze-Lefert, and R. Panstruga. 2005. Recruitment and interaction dynamics of plant penetration resistance components in a plasma membrane microdomain. Proceedings of the National Academy of Sciences of the United States of America 102 (8):3135-3140. doi: 10.1073/pnas.0500012102. abstract

Elliott, C., J. Muller, M. Miklis, R. A. Bhatt, P. Schulze-Lefert, and R. Panstruga. 2005. Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO protein. Biochemical Journal 385:243-254. doi: 10.1042/bj20040993. abstract

Farmer, E.*, and P. Schulze-Lefert*. 2005. Biotic interactions - From molecular networks to inter-organismal communities - Editorial overview. Current Opinion in Plant Biology 8 (4):343-345. doi: 10.1016/j.pbi.2005.05.011. abstract

Freialdenhoven, A.*, J. Orme, T. Lahaye, and P. Schulze-Lefert. 2005. Barley Rom1 reveals a potential link between race-specific and nonhost resistance responses to powdery mildew fungi. Molecular Plant-Microbe Interactions 18 (4):291-299. doi: 10.1094/mpmi-18-0291. abstract

Lipka, V., J. Dittgen, P. Bednarek, R. Bhat, M. Wiermer, M. Stein, J. Landtag, W. Brandt, S. Rosahl, D. Scheel, F. Llorente, A. Molina, J. Parker, S. Somerville, and P. Schulze-Lefert*. 2005. Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis. Science 310 (5751):1180-1183. doi: 10.1126/science.1119409. abstract

Muller, J.*, P. Piffanelli, A. Devoto, M. Miklis, C. Elliott, B. Ortmann, P. Schulze-Lefert*, and R. Panstruga*. 2005. Conserved ERAD-Like quality control of a plant polytopic membrane protein. Plant Cell 17 (1):149-163. doi: 10.1105/tpc.104.026625. abstract

Schulze-Lefert, P.*, and S. Bieri. 2005. Recognition at a distance. Science 308 (5721):506-508. doi: 10.1126/science.1111725. abstract


Bieri, S.*, S. Mauch, Q. H. Shen, J. Peart, A. Devoto, C. Casais, F. Ceron, S. Schulze, H. H. Steinbiss, K. Shirasu, and P. Schulze-Lefert*. 2004. RAR1 positively controls steady state levels of barley MLA resistance proteins and enables sufficient MLA6 accumulation for effective resistance. Plant Cell 16 (12):3480-3495. doi: 10.1105/tpc.104.026682. abstract

Piffanelli, P., L. Ramsay, R. Waugh, A. Benabdelmouna, A. D'Hont, K. Hollricher, J. H. Jorgensen, P. Schulze-Lefert*, and R. Panstruga. 2004. A barley cultivation-associated polymorphism conveys resistance to powdery mildew. Nature 430 (7002):887-891. doi: 10.1038/nature02781. abstract

Sadanandom, A., K. Findlay, J. H. Doonan, P. Schulze-Lefert, and K. Shirasu. 2004. CHPA, a cysteine- and histidine-rich-domain-containing protein, contributes to maintenance of the diploid state in Aspergillus nidulans. Eukaryotic Cell 3 (4):984-991. doi: 10.1128/ec.3.4.984-991.2004. abstract

Schulze-Lefert, P.* 2004. Knocking on heaven's wall: pathogenesis of and resistance to biotrophic fungi at the cell wall. Current Opinion in Plant Biology 7 (4):377-383. doi: 10.1016/j.pbi.2004.05.004. abstract

Schulze-Lefert, P.* 2004. Plant immunity: The origami of receptor activation. Current Biology 14 (1):R22-R24. doi: 10.1016/j.cub.2003.12.017. abstract

Zimmerli, L., M. Stein, V. Lipka, P. Schulze-Lefert, and S. Somerville. 2004. Host and non-host pathogens elicit different jasmonate/ethylene responses in Arabidopsis. Plant Journal 40 (5):633-646. doi: 10.1111/j.1365-313X.2004.02236.x. abstract


Collins, N. C., H. Thordal-Christensen, V. Lipka, S. Bau, E. Kombrink, J. L. Qiu, R. Huckelhoven, M. Stein, A. Freialdenhoven, S. C. Somerville, and P. Schulze-Lefert*. 2003. SNARE-protein-mediated disease resistance at the plant cell wall. Nature 425 (6961):973-977. doi: 10.1038/nature02076. abstract

Devoto, A., H. A. Hartmann, P. Piffanelli, C. Elliott, C. Simmons, G. Taramino, C. S. Goh, F. E. Cohen, B. C. Emerson, P. Schulze-Lefert, and R. Panstruga*. 2003. Molecular phylogeny and evolution of the plant-specific seven-transmembrane MLO family. Journal of Molecular Evolution 56 (1):77-88. doi: 10.1007/s00239-002-2382-5. abstract

Jacobs, A. K., V. Lipka, R. A. Burton, R. Panstruga, N. Strizhov, P. Schulze-Lefert*, and G. B. Fincher. 2003. An Arabidopsis callose synthase, GSL5, is required for wound and papillary callose formation. Plant Cell 15 (11):2503-2513. doi: 10.1105/tpc.016097. abstract

Madsen, L. H., N. C. Collins, M. Rakwalska, G. Backes, N. Sandal, L. Krusell, J. Jensen, E. H. Waterman, A. Jahoor, M. Ayliffe, A. J. Pryor, P. Langridge, P. Schulze-Lefert, and J. Stougaard. 2003. Barley disease resistance gene analogs of the NBS-LRR class: identification and mapping. Molecular Genetics and Genomics 269 (1):150-161. doi: 10.1007/s00438-003-0823-5. abstract

Panstruga, R.*, M. C. Kim, M. J. Cho, and P. Schulze-Lefert. 2003. Testing the efficiency of dsRNAi constructs in vivo: A transient expression assay based on two fluorescent proteins. Molecular Biology Reports 30 (3):135-140. doi: 10.1023/a:1024945920331.  abstract

Panstruga, R.*, and P. Schulze-Lefert. 2003. Corruption of host seven-transmembrane proteins by pathogenic microbes: a common theme in animals and plants? Microbes and Infection 5 (5):429-437. doi: 10.1016/s1286-4579(03)00053-4. abstract

Schulze-Lefert, P.*, and R. Panstruga. 2003. Establishment of biotrophy by parasitic fungi and reprogramming of host cells for disease resistance. Annual Review of Phytopathology 41:641-667. doi: 10.1146/annurev.phyto.41.061002.083300. abstract

Shen, Q. H., F. S. Zhou, S. Bieri, T. Haizel, K. Shirasu, and P. Schulze-Lefert*. 2003. Recognition specificity and RAR1/SGT1 dependence in barley Mla disease resistance genes to the powdery mildew fungus. Plant Cell 15 (3):732-744. doi: 10.1105/tpc.009258. abstract

Shirasu, K.*, and P. Schulze-Lefert*. 2003. Complex formation, promiscuity and multi-functionality: protein interactions in disease-resistance pathways. Trends in Plant Science 8 (6):252-258. doi: 10.1016/s1360-1385(03)00104-3. abstract


Azevedo, C., A. Sadanandom, K. Kitagawa, A. Freialdenhoven, K. Shirasu, and P. Schulze-Lefert. 2002. The RAR1 interactor SGT1, an essential component of R gene-triggered disease resistance. Science 295 (5562):2073-2076. doi: 10.1126/science.1067554. abstract

This work was featured in:

Elliott, C., F. S. Zhou, W. Spielmeyer, R. Panstruga, and P. Schulze-Lefert*. 2002. Functional conservation of wheat and rice Mlo orthologs in defense modulation to the powdery mildew fungus. Molecular Plant-Microbe Interactions 15 (10):1069-1077. doi: 10.1094/mpmi.2002.15.10.1069. abstract

Kim, M. C., S. H. Lee, J. K. Kim, H. J. Chun, M. S. Choi, W. S. Chung, B. C. Moon, C. H. Kang, C. Y. Park, J. H. Yoo, Y. H. Kang, S. C. Koo, Y. D. Koo, J. C. Jung, S. T. Kim, P. Schulze-Lefert, S. Y. Lee, and M. J. Cho. 2002. Mlo, a modulator of plant defense and cell death, is a novel calmodulin-binding protein - Isolation and characterization of a rice Mlo homologue. Journal of Biological Chemistry 277 (22):19304-19314. doi: 10.1074/jbc.M108478200. abstract

Kim, M. C., R. Panstruga, C. Elliott, J. Muller, A. Devoto, H. W. Yoon, H. C. Park, M. J. Cho*, and P. Schulze-Lefert*. 2002. Calmodulin interacts with MLO protein to regulate defence against mildew in barley. Nature 416 (6879):447-450. doi: 10.1038/416447a. abstract

Panstruga, R.*, and P. Schulze-Lefert*. 2002. Live and let live: insights into powdery mildew disease and resistance. Molecular Plant Pathology 3 (6):495-502. doi: 10.1046/j.1364-3703.2002.00145.x.

Piffanelli, P., F. S. Zhou, C. Casais, J. Orme, B. Jarosch, U. Schaffrath, N. C. Collins, R. Panstruga, and P. Schulze-Lefert*. 2002. The barley MLO modulator of defense and cell death is responsive to biotic and abiotic stress stimuli. Plant Physiology 129 (3):1076-1085. doi: 10.1104/pp.010954. abstract

Schulze-Lefert P., Shirasu K., Azevedo C., Piffanelli P., Eilliott C., Zhou F., Panstruga R., Kim M.-C., and Cho, M.-J. (2002) Molecular mechanisms in disease resistance to powdery mildew fungi. In: Biology of plant-microbe interactions Vol. 3, Leong S.A.., Allen C. and Triplett E.W. , Eds., Int. Society for Molecular Plant-Microbe Interactions, St. Paul/Minnesota, pp. 17-22.


Collins, N. C., T. Lahaye, C. Peterhansel, A. Freialdenhoven, M. Corbitt, and P. Schulze-Lefert*. 2001. Sequence haplotypes revealed by sequence-tagged site fine mapping of the Ror1 gene in the centromeric region of barley chromosome 1H. Plant Physiology 125 (3):1236-1247. doi: 10.1104/pp.125.3.1236. abstract

Halterman, D., F. S. Zhou, F. S. Wei, R. P. Wise*, and P. Schulze-Lefert. 2001. The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria graminis f. sp hordei in barley and wheat. Plant Journal 25 (3):335-348. doi: 10.1046/j.1365-313x.2001.00982.x. abstract

Kurth, J., R. Kolsch, V. Simons, and P. Schulze-Lefert*. 2001. A high-resolution genetic map and a diagnostic RFLP marker for the Mlg resistance locus to powdery mildew in barley. Theoretical and Applied Genetics 102 (1):53-60. doi: 10.1007/s001220051617. abstract

Zhou, F. S., J. C. Kurth, F. S. Wei, C. Elliott, G. Vale, N. Yahiaoui, B. Keller, S. Somerville, R. Wise, and P. Schulze-Lefert*. 2001. Cell-autonomous expression of barley Mla1 confers race-specific resistance to the powdery mildew fungus via a Rar1-independent signaling pathway. Plant Cell 13 (2):337-350. doi: 10.1105/tpc.13.2.337. abstract


Schulze-Lefert, P.*, and J. Vogel. 2000. Closing the ranks to attack by powdery mildew. Trends in Plant Science 5 (8):343-348. doi: 10.1016/s1360-1385(00)01683-6. abstract

Schweizer, P., J. Pokorny, P. Schulze-Lefert, and R. Dudler. 2000. Double-stranded RNA interferes with gene function at the single-cell level in cereals. Plant Journal 24 (6):895-903. doi: 10.1046/j.1365-313x.2000.00941.x. abstract

Shirasu, K., A. H. Schulman, T. Lahaye, and P. Schulze-Lefert*. 2000. A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion. Genome Research 10 (7):908-915. doi: 10.1101/gr.10.7.908. abstract

Shirasu, K., and P. Schulze-Lefert*. 2000. Regulators of cell death in disease resistance. Plant Molecular Biology 44 (3):371-385. doi: 10.1023/a:1026552827716. abstract


Devoto, A., P. Piffanelli, I. Nilsson, E. Wallin, R. Panstruga, G. von Heijne, and P. Schulze-Lefert*. 1999. Topology, subcellular localization, and sequence diversity of the Mlo family in plants. Journal of Biological Chemistry 274 (49):34993-35004. doi: 10.1074/jbc.274.49.34993. abstract

Leister, D., J. Kurth, D. A. Laurie, M. Yano, T. Sasaki, A. Graner, and P. Schulze-Lefert. 1999. RFLP- and physical mapping of resistance gene homologues in rice (O-sativa) and barley (H-vulgare). Theoretical and Applied Genetics 98 (3-4):509-520. doi: 10.1007/s001220051099. abstract

Piffanelli, P., A. Devoto, and P. Schulze-Lefert*. 1999. Defence signalling pathways in cereals. Current Opinion in Plant Biology 2 (4):295-300. doi: 10.1016/s1369-5266(99)80052-1. abstract

Shirasu, K., T. Lahaye, M. W. Tan, F. S. Zhou, C. Azevedo, and P. Schulze-Lefert*. 1999. A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C-elegans. Cell 99 (4):355-366. doi: 10.1016/s0092-8674(00)81522-6. abstract

Shirasu, K., K. Nielsen, P. Piffanelli, R. Oliver, and P. Schulze-Lefert*. 1999. Cell-autonomous complementation of mlo resistance using a biolistic transient expression system. Plant Journal 17 (3):293-299. doi: 10.1046/j.1365-313X.1999.00376.x. abstract

Wei, F. S., K. Gobelman-Werner, S. M. Morroll, J. Kurth, L. Mao, R. Wing, D. Leister, P. Schulze-Lefert, and R. P. Wise. 1999. The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppressed recombination within a 240-kb DNA interval on chromosome 5S (1HS) of barley. Genetics 153 (4):1929-1948. abstract


Lahaye, T., S. Hartmann, S. Topsch, A. Freialdenhoven, M. Yano, and P. Schulze-Lefert*. 1998. High-resolution genetic and physical mapping of the Rar1 locus in barley. Theoretical and Applied Genetics 97 (4):526-534. doi: 10.1007/s001220050927. abstract

Lahaye, T., K. Shirasu, and P. Schulze-Lefert*. 1998. Chromosome landing at the barley Rar1 locus. Molecular and General Genetics 260 (1):92-101. doi: 10.1007/s004380050874. abstract

Leister, D., J. Kurth, D. A. Laurie, M. Yano, T. Sasaki, K. Devos, A. Graner, and P. Schulze-Lefert*. 1998. Rapid reorganization of resistance gene homologues in cereal genomes. Proceedings of the National Academy of Sciences of the United States of America 95 (1):370-375. doi: 10.1073/pnas.95.1.370. abstract

Panstruga, R., R. Buschges, P. Piffanelli, and P. Schulze-Lefert*. 1998. A contiguous 60 kb genomic stretch from barley reveals molecular evidence for gene islands in a monocot genome. Nucleic Acids Research 26 (4):1056-1062. doi: 10.1093/nar/26.4.1056. abstract

Spielmeyer, W., M. Robertson, N. Collins, D. Leister, P. Schulze-Lefert, S. Seah, O. Moullet, and E. S. Lagudah. 1998. A superfamily of disease resistance gene analogs is located on all homoeologous chromosome groups of wheat (Triticum aestivum). Genome 41 (6):782-788. doi: 10.1139/g98-083. abstract

von Röpenack, E., A. Parr, and P. Schulze-Lefert*. 1998. Structural analyses and dynamics of soluble and cell wall-bound phenolics in a broad spectrum resistance to the powdery mildew fungus in barley. Journal of Biological Chemistry 273 (15):9013-9022. doi: 10.1074/jbc.273.15.9013. abstract


Büschges, R., K. Hollricher, R. Panstruga, G. Simons, M. Wolter, A. Frijters, R. vanDaelen, T. vanderLee, P. Diergaarde, J. Groenendijk, S. Topsch, P. Vos, F. Salamini, and P. Schulze-Lefert*. 1997. The barley mlo gene: A novel control element of plant pathogen resistance. Cell 88 (5):695-705. doi: 10.1016/s0092-8674(00)81912-1. abstract

Peterhansel, C., A. Freialdenhoven, J. Kurth, R. Kolsch, and P. Schulze-Lefert*. 1997. Interaction analyses of genes required for resistance responses to powdery mildew in barley reveal distinct pathways leading to leaf cell death. Plant Cell 9 (8):1397-1409. abstract

Schiffer, R., R. Gorg, B. Jarosch, U. Beckhove, G. Bahrenberg, K. H. Kogel*, and P. Schulze-Lefert*. 1997. Tissue dependence and differential cordycepin sensitivity of race-specific resistance responses in the barley powdery mildew interaction. Molecular Plant-Microbe Interactions 10 (7):830-839. doi: 10.1094/mpmi.1997.10.7.830. abstract

Simons, G., T. vanderLee, P. Diergaarde, R. vanDaelen, J. Groenendijk, A. Frijters, R. Buschges, K. Hollricher, S. Topsch, P. Schulze-Lefert, F. Salamini, M. Zabeau, and P. Vos. 1997. AFLP-based fine mapping of the Mlo gene to a 30-kb DNA segment of the Barley genome. Genomics 44 (1):61-70. doi: 10.1006/geno.1997.4844. abstract


Freialdenhoven, A., C. Peterhansel, J. Kurth, F. Kreuzaler, and P. Schulze-Lefert*. 1996. Identification of genes required for the function of non-race-specific mlo resistance to powdery mildew in barley. Plant Cell 8 (1):5-14. doi: 10.2307/3870064. abstract

Lahaye, T., B. Rueger, S. Toepsch, J. Thalhammer, and P. Schulze-Lefert. 1996. Detection of single-copy sequences with digoxigenin-labeled probes in a complex plant genome after separation on pulsed-field gels. Biotechniques 21 (6):1067-+. abstract


Schulze-Lefert P. (1995) Isolation of genes for resistance in plants. In: Novel approaches to integrated pest mangement, Reuveni R., Ed., CRC Press, Inc., USA, pp. 47-74.

Skadsen, R. W., P. Schulze-Lefert, and J. M. Herbst. 1995. Molecular cloning, characterization and expression analysis of two catalase isozyme genes in barley. Plant Molecular Biology 29 (5):1005-1014. doi: 10.1007/bf00014973. abstract


Freialdenhoven, A., B. Scherag, K. Hollricher, D. B. Collinge, H. Thordalchristensen, and P. Schulze-Lefert*. 1994.  Nar-1 and Nar-2, Two Loci Required for Mla12-Specified Race-Specific Resistance to Powdery Mildew in Barley. Plant Cell 6 (7):983-994. abstract

Merkle, T., H. Frohnmeyer, P. Schulze-Lefert, J. L. Dangl, K. Hahlbrock, and E. Schafer. 1994. Analysis of the parsley chalcone-synthase promoter in response to different light qualities. Planta 193 (2):275-282.abstract

Schulze-Lefert P., Freialdenhoven A., Scherag B., and Görg R. (1994) Dissection of resistance pathways to powdery mildew attack. In: Advances in molecular genetics of plant-microbe interactions Vol. III, Daniels, M.J., Downie, J.A., Osbourn, A.E., Eds., Kluwer Academic Publishers Dordrecht/Boston/London, pp. 309-312.


Görg, R., K. Hollricher, and P. Schulze-Lefert*. 1993. Functional analysis and RFLP-mediated mapping of the Mlg resistance locus in barley. Plant Journal 3 (6):857-866. doi: 10.1046/j.1365-313X.1993.03060857.x. abstract

Görg R., Hollricher K., and Schulze-Lefert P (1993) Functional analysis of the Mlg resistance locus in barley. In: Mechanisms of plant defense response Vol. II, Fritig B. and Legrand M., Eds., Kluwer Academic Publishers Dordrecht/Boston/London, pp. 45-48.

Wolter, M., K. Hollricher, F. Salamini, and P. Schulze-Lefert*. 1993.  The mlo resistance alleles to powdery mildew infection in barley trigger a developmentally controlled defence mimic phenotype. Molecular & General Genetics 239 (1-2):122-128. doi: 10.1007/bf00281610. abstract


Becker-André, M., P. Schulze-Lefert, and K. Hahlbrock. 1991. Structural comparison, modes of expression, and putative cis-acting elements of the two 4-coumarate: CoA ligase genes in potato. Journal of Biological Chemistry 266 (13):8551-8559. abstract

Hauffe, K. D., U. Paszkowski, P. Schulze-Lefert, K. Hahlbrock, J. L. Dangl, and C. J. Douglas. 1991. A parsley 4CL-1 promoter fragment specifies complex expression patterns in transgenic tobacco.. Plant Cell 3 (5):435-443. doi: 10.1105/tpc.3.5.435. abstract

Hinze, K., R. D. Thompson, E. Ritter, F. Salamini, and P. Schulze-Lefert*. 1991. Restriction fragment length polymorphism-mediated targeting of the ml-o resistance locus in barley (Hordeum vulgare). Proceedings of the National Academy of Sciences of the United States of America 88 (9):3691-3695. doi: 10.1073/pnas.88.9.3691. abstract

Weißhaar B., Block A., Armstrong G.A., Herrmann A., Schulze-Lefert P., and Hahlbrock K. (1991) Regulatory elements required for light-mediated expression of the Petroselinum crispum chalcone synthase gene. In: Molecular Biology of Plant Development Vol. 45, Jenkins G.I., Schuch W., Eds., Cambridge UK, pp. 191-210.


Block, A., J. L. Dangl, K. Hahlbrock, and P. Schulze-Lefert*. 1990.  Functional borders, genetic fine structure, and distance requirements of cis elements mediating light responsiveness of the parsley chalcone synthase promoter. Proceedings of the National Academy of Sciences of the United States of America 87 (14):5387-5391. doi: 10.1073/pnas.87.14.5387. abstract


Schulze-Lefert, P., M. Becker-André, W. Schulz, K. Hahlbrock, and J. L. Dangl. 1989.  Functional architecture of the light-responsive chalcone synthase promoter from parsley. Plant Cell 1 (7):707-714. doi: 10.1105/tpc.1.7.707. abstract

Schulze-Lefert, P., J. L. Dangl, M. Becker-André, K. Hahlbrock, and W. Schulz. 1989.  Inducible in vivo DNA footprints define sequences necessary for UV light activation of the parsley chalcone synthase gene . Embo Journal 8 (3):651-656. doi: 10.1002/j.1460-2075.1989.tb03422.x. abstract

Go to Editor View