Publications

Our research ranks among the top 1% most cited works across several different fields

2023

Ordon, J., Kiel, N., Becker, D., Kretschmer, C., Schulze-Lefert, P., Stuttmann, J. (2023) Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two. Plant Methods, in press.

Getzke, F.^§, Amine Hassani, M^.§, Crüsemann, M., Malisic, M., Zhang, P., Ishigaki, Y., Böhringer, N., Jiménez Fernández, A., Wang, L., Ordon, J., Ma, K.-W., Thiergart, T., Harbort, C. J., Wesseler, H., Miyauchi, S., Garrido-Oter, R., Shirasu, K., Schäberle, T. F., Hacquard, S.^#, Schulze-Lefert, P.^# (2023) Co-functioning of bacterial exometabolites drives root microbiota establishment. PNAS, doi: 10.1073/pnas.2221508120. abstract
^§equal contribution authors ^#corresponding authors

2022

Förderer, A.^§, Li, E.^§, Lawson, A. W.^§, Deng, Y.-N.^§, Sun, Y., Logemann, E., Zhang, X., Wen, J., Han, Z., Chang, J., Chen, Y.^#, Schulze-Lefert, P.^#, Chai, J.^# (2022) A wheat resistosome defines common principles of immune receptor channels. Nature 610, 532–539 (2022), doi: 10.1038/s41586-022-05231-w. abstract
^§equal contribution authors ^#corresponding authors

This work was featured by: Outram, M.A., Dodds, P.N. Wheeling in a new era in plant immunity. Nat. Plants 8, 1142–1143 (2022). https://doi.org/10.1038/s41477-022-01257-0

Acevedo-Garcia, J., Walden, K., Leissing, F., Baumgarten, K., Drwiega, K., Kwaaitaal, M., Reinstädler, A., Freh, M., Dong, X., James, G.V., Baus, L.C., Mascher, M., Stein, N., Schneeberger, K., Brocke-Ahmadinejad, N., Kollmar, M., Schulze-Lefert, P., Panstruga, R. (2022) Barley Ror1 encodes a class XI myosin required for mlo-based broad-spectrum resistance to the fungal powdery mildew pathogen. Plant Journal 112: 84-103, doi: 10.1111/tpj.15930. abstract

Meyer, F., et al (2022). Critical Assessment of Metagenome Interpretation: the second round of challenges. Nature Methods 19(4):429-440, doi: 10.1038/s41592-022-01431-4. abstract

Yu, D., Song, W., Tan, E. Y. J., Liu, L., Cao, Y., Jirschitzka, J., Li, E., Logemann, E., Xu, C., Huang, S., Jia, A., Chang, X., Han, Z., Wu, B., Schulze-Lefert, P., Chai, J. (2022) TIR domains of plant immune receptors are 2’,3’-cAMP/cGMP synthetases mediating cell death. Cell 185: 2370-2386.e18, doi: 10.1016/j.cell.2022.04.032. abstract

This work was featured by: Tian L, Li X. TIR domains as two-tiered enzymes to activate plant immunity. Cell. 2022 Jun 23;185(13):2208-2209. doi: 10.1016/j.cell.2022.05.025.

Bourceret, A. ^#, Guan, R. ^#, Dorau, K., Mansfeldt, T., Omidbakhshfard, A., Medeiros, D. B., Fernie, A. R., Hofmann, J., Sonnewald, U., Mayer, J., Gerlach, N., The RECONSTRUCT consortium, Bucher, M., Garrido-Oter, R. ^*, Spaepen, S. ^*, Schulze-Lefert, P.^* (2022) Maize field study reveals covaried microbiota and metabolic changes in roots over plant growth. mBio 13: e02584-21, doi: 10.1128/mbio.02584-21. abstract
^#contributed equally, ^*co-corresponding authors

Ma, K.-W., Ordon, J., Schulze-Lefert, P. (2022) Gnotobiotic plant systems for reconstitution and functional studies of the root microbiota. Current Protocols 2, d362. doi: 10.1002/cpz1.362. abstract

Saur, I.M.L., Lawson, A.W. & Schulze-Lefert, P. (2022) Buy one, get two. Nature Plants 8: 100–101 (2022), doi: 10.1038/s41477-022-01097-y. abstract

2021

Durán, P.,Reinstädler, R., Rajakrut, A.-L., Hashimoto, H., Garrido-Oter, R., Paul Schulze-Lefert, P. Panstruga, R. (2021) A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota. Environmental Microbiology 23: 6292-6308, doi: 10.1111/1462-2920.15768. abstract

Wippel, K.^†, Tao, K.^†, Niu, Y., Zgadzaj, R., Kiel, N., Guan, R., Dahms, E., Zhang, P., Jensen, D. B., Logemann, E., Radutoiu, S.*, Schulze-Lefert, P.*, Garrido-Oter, R.* (2021) Host preference and invasiveness of commensal bacteria in the Lotus and Arabidopsis root microbiota. Nature Microbiology, 6: 1150–1162, doi: 10.1038/s41564-021-00941-9. abstract
^†co-first authors, *co-corresponding authors

This work is recommended by facultyopinions.com
This work was featured in Nature Microbiology | VOL 6 | September 2021 | 1103–1104 | by A. M. O’Brien and T. L. Harrison “Host match improves root microbiome growth”

Schütz, V., Frindte, K., Cui, J., Zhang, P., Hacquard, S., Schulze-Lefert, P., Knief, C., Schulz, M. and Dörmann, P. (2021) Differential Impact of Plant Secondary Metabolites on the Soil Microbiota. Frontiers in Microbiology 12: 1267, doi: 10.3389/fmicb.2021.666010 abstract

Ma, K.-W. *, Niu, Y., Yong, J.*, Ordon, J.*, Copeland, C., Emonet, A., Geldner, N., Guan, R., Stolze, S.C., Nakagami, H., Garrido-Oter, R.^†, Schulze-Lefert, P.^† (2021) Coordination of microbe-host homeostasis by crosstalk with plant innate immunity. Nature Plants, doi: 10.1038/s41477-021-00920-2. abstract
*contributed equally to this work † corresponding authors

Winkelmüller, T. M.^*, Entila, R.^*, Anver, S.^*, Piasecka, A., Song, B., Dahms, E., Sakakibara, H., Gan, X., Kulak, K., Sawikowska, A., Krajewski, P., Tsiantis, M., Garrido-Oter, R., Fukushima, K., Schulze-Lefert, P., Laurent, S., Bednarek, P. and Tsuda, K. (2021) Gene expression evolution in plant immunity, Plant Cell, koab073, doi: 10.1093/plcell/koab073. abstract ^*contributed equally to this work

Kremer, J. M., Sohrabi, R., Paasch, B. C., Rhodes, D., Thireault,, C., Schulze-Lefert, P., Tiedje, J. M., He, S. Y. (2021) Peat-based gnotobiotic plant growth systems for Arabidopsis microbiome research. Nature Protocols 16, 2450–2470, doi: 10.1038/s41596-021-00504-6. abstract

Emonet, A., Zhou, F., Vacheron, J., Heiman, C. M., Dénervaud Tendon, V., Ma, K.-W., Schulze-Lefert, P., Keel, C., Geldner, N. (2021) Spatially Restricted Immune Responses Are Required for Maintaining Root Meristematic Activity upon Detection of Bacteria, Current Biology 31: 1012-1028.e7, doi: 10.1016/j.cub.2020.12.048. abstract

Bauer, S., Yu, D., Lawson, A. W., Saur, I. M. L., Frantzeskakis, L., Kracher, B., Logemann, E., Chai, J., Maekawa, T., Schulze-Lefert, P. (2021) The leucine-rich repeats in allelic barley MLA immune receptors define specificity towards sequence-unrelated powdery mildew avirulence effectors with a predicted common RNase-like fold. PLoS Pathogens 17(2): e1009223. doi:doi.org/10.1371/journal.ppat.1009223. abstract

Saur, I.M.L., Panstruga R., and Schulze-Lefert*, P. (2021) NOD-like receptor (NLR)-mediated plant immunity: from structure to cell death. Nature Reviews Immunology, 21, 305–318, DOI: 10.1038/s41577-020-00473-z. abstract

Zhang, J., Liu, Y-X., Guo, X., Qin, Y., Garrido-Oter, R., Schulze-Lefert, P., Bai, Y. (2021) High-throughput cultivation and identification of bacteria from the plant root microbiota. Nature Protocols 16: 988-1012, doi: 10.1038/s41596-020-00444-7. abstract

2020

Harbort, C. J., Hashimoto, J., Inoue, H., Schulze-Lefert, P. (2020) A gnotobiotic growth assay for Arabidopsis root microbiota reconstitution under iron limitation. STAR Protocols 15;1(3):100226, doi: 10.1016/j.xpro.2020.100226. abstract

Frerigmann, H.; Piotrowski, M.; Lemke, R.; Bednarek, P.; Schulze-Lefert^,P. (2020) A network of phosphate starvation and immune-related signaling and metabolic pathways controls the interaction between Arabidopsis thaliana and the beneficial fungus Colletotrichum tofieldiae. Molecular Plant Microbe Interactions, doi: 10.1094/MPMI-08-20-0233-R. abstract

Ma, S.†, Lapin, D.†, Liu, L.†, Sun,Y.†, Song, W.†, Zhang, X., Logemann, E., Yu, D., Wang, J., Jirschitzka, J., Han, Z., Schulze-Lefert, P.*, Parker, J.E.*, Chai, J.* (2020) Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science 370, 6521, eabe3069, doi: 10.1126/science.abe3069, *corresponding authors, †equal contributions abstract

Harbort, C. J., Hashimoto, M., Inoue, H., Niu, Y., Guan, R., Rombolà, A. D., Kopriva, S., Voges, M. J. E. E. E., Sattely, E. S., Garrido-Oter, R., Schulze-Lefert, P. (2020) Root-secreted coumarins and the microbiota interact to improve iron nutrition in Arabidopsis. Cell Host & Microbe 28, 825-837, doi: 10.1016/j.chom.2020.09.006. abstract

Mahdi, L., Huang, M., Zhang, X., Nakano, R. T., Kopp, L. B., Saur, I. M. L., Jacob, F., Kovacova, V., Lapin, D., Parker, J.E., Murphy, J. M., Hofmann, K., Schulze-Lefert, P., Chai, J., Maekawa, T. (2020) Innate immune signalling by plant mixed lineage kinase domain-like proteins. Cell Host & Microbe 28, 813-824e, doi 10.1016/j.chom.2020.08.012. abstract

Nakano, R.T., Ishihama, N., Wang, Y,, Takagi, J., Uemura, T., Schulze-Lefert, P., Nakagami, H. (2020) Apoplastic fluid preparation from Arabidopsis thaliana leaves upon interaction with a non-adapted powdery mildew pathogen, Methods in Molecular Biology, 2139:79-88 (2020), doi: 10.1007/978-1-0716-0528-8_6. abstract

Hematy, K.*, Lim, M.*, Cherk, C., Piślewska-Bednarek, M., Sanchez-Rodriguez, C., Stein, M., Fuchs, R., Klapprodt, C., Lipka, V., Molina, A., Grill, E., Schulze-Lefert, P., Bednarek, P., Somerville, S. (2020) Moonlighting function of Phytochelatin synthase1 in extracellular defense against fungal pathogens. Plant Physiology 120: 1-13, doi:10.1104/pp.19.01393. *contributed equally abstract

Copeland, C.; Schulze-Lefert, P. (2020) Leaf-derived bacterial communities adapt to the local environment. PNAS 117: 808-810, doi: 10.1073/pnas.1920431117 (see companion article 10.1073/pnas.1908600116) abstract

Thiergart, T.^§, Durán, P^§., Ellis, T., Vannier, N., Garrido-Oter, R., Roux, F., Alonso-Blanco, C., Ågren*, J., Schulze-Lefert, P.*, Hacquard, S.* (2020) Root microbiota assembly and adaptive differentiation among European Arabidopsis populations. Nature Ecology & Evolution 4:122-131, doi:10.1038/s41559-019-1063-3 . ^§ joint first authors, ^*co-corresponding authors abstract

2019

Saur, I.M.-L., Bauer, S., Lu, X., Schulze-Lefert, P. (2019) A cell death assay in barley and wheat protoplasts for identification and validation of matching pathogen AVR effector and plant NLR immune receptors. Plant Methods 15: 118, doi:10.1186/s13007-019-0502-0. abstract

Thiergart, T.^§, Zgadzaj, R.^§, Bozsóki, Z., Garrido-Oter, R., Radutoiu, S.^*, and Schulze-Lefert, P.^* (2019) Lotus japonicus symbiosis genes impact microbial interactions between symbionts and multikingdom commensal communities. mBio 10:e01833-19, doi: 10.1128/mBio.01833-19. ^§ joint first authors, ^*co-corresponding authors abstract

Wippel, K., Schulze-Lefert, P.*, Garrido-Oter, R.*: Rhizobien in der Pflanzenmikrobiota: Evolution der Wurzelknöllchensymbiose und Funktionen der Mikrobiota für den Pflanzenwirt. Biologie in unserer Zeit 6 (49) , 426-434 (2019). *co-corresponding authors

Voges, M.J.E.E.E., Bai, Y., Schulze-Lefert, P., Sattely, E. S. (2019) Plant derived coumarins shape the composition of an Arabidopsis synthetic root microbiome. PNAS 116 (25) 12558-12565, doi 10.1073/pnas.1820691116. abstract

Saur, I. M. L., Bauer, S., Kracher, B., Lu, X, Frantzeskakis, L., Müller, M. C., Sabelleck, B., Kümmel, F., Panstruga, R., Maekawa, T., Schulze-Lefert, P. (2019) Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism. eLife 8:e44471, doi: 10.7554/eLife.44471. abstract

Berens, M. L., Wolinska, K. W., Spaepen, S., Ziegler, J., Nobori, T., Nair, A., Krüler, K., Winkelmueller, T. M., Wang, Y., Mine, A., Becker, D., Garrido-Oter, R., Schulze-Lefert, P.*, Tsuda, K.* (2019) Balancing trade-offs between biotic and abiotic stress responses through leaf age-dependent variation in stress hormone cross-talk. Proceedings of the National Academy of Sciences of the United States of America 116: 2364-2373, doi:10.1073/pnas.1817233116. abstract

Maekawa, T.*§ , Kracher, B.*, Saur, I. M. L., Yoshikawa-Maekawa, M., Kellner, R., Pankin, A., von Korff, M., Schulze-Lefert, P. (2019) Subfamily-specific specialization of RGH1/MLA immune receptors in wild barley. Molecular Plant-Microbe Interactions 32, 107-119, doi: 10.1094/MPMI-07-18-0186-FI. * joint first authors, §corresponding author. abstract

Uemura, T.*^§, Nakano, R. T.*, Takagi, J., Wang, Y., Kramer, K., Finkemeier, I., Nakagami, H., Tsuda, K., Ueda, T., Schulze-Lefert, P.^§, Nakano, S.: The Golgi-released independent trans-Golgi network (GI-TGN) mediates the protein secretory pathway that is needed for extracellular delivery of cell wall modification enzymes. Plant Physiology 179: 519-532 (2019). *contributed equally, ^§co-corresponding authors. abstract

2018

Durán, P., Thiergart, T., Garrido-Oter, R., Agler, M., Kemen, E., Schulze-Lefert, P.*, Hacquard, S.* (2018) Microbial interkingdom interactions in roots promote Arabidopsis survival. Cell 175, 973-983, doi: 10.1016/j.cell.2018.10.020 . *co-corresponding authors abstract

Wibowo, A. Becker, C., Durr, J., Price, J., Spaepen, S., Hilton, S., Putra, H., Papareddy, R., Saintain, Q., Harvey, S., Bending, G., Schulze-Lefert, P., Weigel, D., Gutiérrez-Marcos, J. (2018) Partial maintenance of organ-specific epigenetic marks during plant asexual reproduction leads to heritable phenotypic variation. PNAS 115(39):E9145-E9152. abstract

Garrido-Oter, R., Nakano, R. T., Dombrowski, N., Ma, K.-W., The AgBiome Team, McHardy, A. C. and P. Schulze-Lefert: Modular traits of the Rhizobiales root microbiota and their evolutionary relationship with symbiotic rhizobia. Cell Host & Microbe 24, 155–167 (2018). abstract

This work was featured in: Willige, B.C., Chory, J, Burger M. Next generation of Plant-Associated Bacterial Genome Data. Cell Host & Microbe 24: 10-11 (2018). DOI: 10.1016/j.chom.2018.06.009

Frantzeskakis, L.^§; Kracher, B.^§; Kusch, S.; Yoshikawa-Maekawa, M.; Bauer, S.; Pedersen, C.; Spanu, P.; Maekawa, T.*; Schulze-Lefert, P.*; Panstruga, R.* (2018) Signatures of host specialization and a recent transposable element burst in the dynamic one-speed genome of the fungal barley powdery mildew pathogen. BMC Genomics 19, 381 (2018), doi: 10.1101/246280 . ^§joint first authors; *co-corresponding authors. abstract

Jacob, F., Kracher, B., Mine, A., Seyfferth, C., Blanvillain-Baufumé, S., Parker, J.E., Tsuda, K., Schulze-Lefert, P., Maekawa, T., A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytologist 217, 1667-1680 (2018), doi: 10.1111/nph.14943 abstract

Piślewska‐Bednarek, M., Nakano, R.T., Hiruma, K., Pastorczyk, M., Sanchez‐Vallet, A., Singkaravanit‐Ogawa, S., Ciesiołka, D., Takano, Y., Molina, A., Schulze‐Lefert, P., Bednarek, P. Glutathione transferase U13 functions in pathogen‐triggered glucosinolate metabolism in Arabidopsis. Plant Physiology 176, 538–551 (2018), doi: 10.1104/pp.17.01455. abstract

Robbins, C., Thiergart, T., Hacquard, S., Garrido-Oter, R., Gans, W., Peiter, E., Schulze-Lefert, P.*, Spaepen, S.*: Root-associated bacterial and fungal community profiles of Arabidopsis thaliana are robust across contrasting soil P levels. Phytobiomes 2, 24-34 (2018), doi: 10.1094/PBIOMES-09-17-0042-R . *co-corresponding authors abstract

Sopeña-Torres, S.; Jorda, L.; Sanchez-Rodriguez, C.; Miedes, E.; Escudero, V.; Swamy, S.; Lopez, G.; Pislewska-Bednarek, M.; Lassowskat, I.; Lee, J.; Gu, Y.; Haigis, S.; Alexander, D.; Pattathil, S.; Muñoz-Barrios, A.; Bednarek, P.; Somerville, S.; Schulze-Lefert, P.; Hahn, M.; Scheel, D.; Molina, A. YODA MAP3K kinase regulates plant immune responses conferring broad-spectrum disease resistance. New Phytologist 218, 661-680 (2018), doi:10.1111/nph.15007. abstract

2017

Dombrowski, N., Schlaeppi, K., Agler, M., Hacquard, S., Kemen, E., Garrido Oter, R., Wunder, J., Coupland, G. and Schulze-Lefert, P., Root microbiota dynamics of perennial Arabis alpina are dependent on soil residence time but independent of flowering time. ISME Journal 11, 43–55, doi:10.1038/ismej.2016.109 (2017). abstract

Fukunaga, S., Sogame, M., Hata, M., Singkaravanit-Ogawa, S., Piślewska-Bednarek, M., Onozawa-Komori, M., Nishiuchi, T., Hiruma, K., Saitoh, H., Terauchi, R., Kitakura, S., Inoue, Y., Bednarek, P., Schulze-Lefert, P., Takano, Y. Dysfunction of Arabidopsis MACPF domain protein activates programmed cell death via tryptophan metabolism in MAMP-triggered immunity. Plant J., 89, 381-393, doi: 10.1111/tpj.13391 (2017). abstract

Hacquard, S., Spaepen, S., Garrido‐ Oter R. and Schulze ‐Lefert, P. Interplay between innate immunity and the plant microbiota. Annu. Rev. Phytopathol. 55, 565-589, doi: 10.1146/annurev-phyto-080516-035623 (2017). abstract

Maekawa, T., Schulze-Lefert, P. (2017) Caught in the jump. Science 357, 31-32, doi: 10.1126/science.aan8287. abstract

Nakano, R.T., Pilewska-Bednarek, M., Yamada, K., Edger, P., Miyahara, M., Kondo, M., Böttcher, C., Mori, M., Nishimura, M., Schulze-Lefert*, P., Hara-Nishimura*, I. and Bednarek* P. PYK10 Myrosinase Reveals a Functional Coordination between ER Bodies and Glucosinolates in Arabidopsis thaliana. Plant J., Plant J. 89: 204–220, doi : 10.1111/tpj.13377 (2017). *co-corresponding author. abstract

Sczyrba, A.*, Hofmann, P.*, Belmann, P*., Koslicki, D., Janssen, S., Dröge, J., Gregor, I., Majda, S., Fiedler, J., Dahms, E., Bremges, A., Fritz, A., Garrido-Oter, R., Sparholt Jørgensen, T., Shapiro, N., Blood, P. D., Gurevich, A., Bai, Y., Tuarev, D., DeMaere, M. Z., Chikhi, R., Nagarajan, N., Hestbjerg Hansen, L., Sørensen, S. J., Chia, B. K. H., Denis, B., Froula, J. L., Wang, Z., Egan, R., Don Kang, D., Cook, J., Deltel, C., Beckstette, M., Lemaitre, C., Peterlongo, P., Rizk, G., Lavenier, D., Wu, Y.-W., Singer, S. W., Jain, C., Strous, M., Klingenberg, H., Meinicke, P., Barton, M., Lingner, T., Lin, H.-H., Liao, Y.-C., Silva, G. G. Z., Cuevas, D. A., Edwards, R. A., Saha, S., Piro, V. C., Renard, B. Y., Hill, C. M., Pop, M., Klenk, H.-P., Goeker, M., Kyrpides, N., Woyke, T., Vorholt, J., Schulze-Lefert, P., Rubin, E. M., Darling, A. E., Rattei, T., McHardy, A. C. Critical Assessment of Metagenome Interpretation – a comprehensive benchmark of computational metagenomics software. Nature Methods 14, 1063–1071, doi: 10.1038/nmeth.4458 (2017). * contributed equally. abstract

2016

Hacquard, S., Kracher, B., Hiruma, K, Münch, P. C., Garrido-Oter, R. Thon, M. R., Weimann, A., Damm, U., Dallery, J.-F., Hainaut, M., Henrissat, B., Lespinet, O., Sacristán, S., Ver Loren van Themaat, E., Kemen, E., McHardy, A.C., Schulze-Lefert, P.*, O’Connell, R. J.* Survival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi. Nature Communications 7: 11362, doi: 10.1038/ncomms11362 (2016). *Corresponding authors absctract

Hiruma, K., Gerlach, N., Sacristán, S., Nakano, R. T., Hacquard, S., Kracher, B., Neumann, U., Ramírez, D., Bucher, M, O’Connell, R.* and Schulze-Lefert, P.* Root endophyte Colletotrichum tofieldiae confers plant fitness benefits that are phosphate status-dependent. Cell 165, 464-474 (2016), published online 17 March 2016, doi:10.1016/j.cell.2016.02.028. *Corresponding authors
abstract

This work was featured in: Cell 165, 269-271 (2016) by Louisa M. Liberman and Philip N. Benfey: A Friend in Need (of Nutrients) Is a …
This article has been recommended by Faculty 1000:

Lu, X., Kracher, B., Saur, I.M.-L., Bauer, S., Ellwood, S.R., Wise, R., Yaeno, T., Maekawa, T., and Schulze-Lefert, P.: Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen. PNAS 113 (42), E6486–E6495, doi: 10.1073/pnas.1612947113 (2016) abstract

Zgadzaj^#, R., Garrido-Oter^#, R., Jensen, D.B., Schulze-Lefert* P. and Radutoiu* S. Root nodule symbiosis in Lotus japonicus drives the establishment of distinctive rhizosphere, root, and nodule bacterial communities. PNAS 113 (49), E7996–E800, DOI: 10.1073/pnas.1616564113 (2016). ^#joint first authors, *co-corresponding authors abstract

2015

Bai, Y., Müller, D. B., Srinivas, G., Garrido-Oter, R., Potthoff, E., Rott, M., Dombrowski, N., Münch, P.C., Spaepen, S., Remus-Emsermann, M., Hüttel, B., McHardy, A., Vorholt, J.A., and Schulze-Lefert, P. Functional overlap of the Arabidopsis leaf and root microbiota. Nature 528, 364-369 (2015), doi:10.1038/nature16192.
abstract

This work was featured in: Nature (2015), doi:10.1038/nature16319, by Gwyn A. Beattie: Microbiomes: Curating communities from plants

Lu, X., Dittgen, J., Pislewska-Bednarek, M., Molina, A., Schneider, B., Svatos, A., Doubsky, J., Schneeberger, K., Weigel, D., Bednarek, P. and Schulze-Lefert, P. Mutant allele-specific uncoupling of PEN3 functions reveals engagement of the ABC transporter in distinct tryptophan metabolic pathways. Plant Physiology 168, 814-27 doi:10.1104/pp.15.00182 (2015).
(abstract)

Hacquard, S., Garrido-Oter, R., González, A., Spaepen, S., Ackermann, G., Lebeis, S., McHardy, A. C., Dangl, J. L., Knight, R., Ley, R., Schulze-Lefert, P. Microbiota and Host Nutrition across Plant and Animal Kingdoms.Cell Host & Microbe 17, 603-616 (2015).
(abstract)

Bulgarelli, D., Carrido-Oter, R., Münch, P. C., Weiman, A., Dröge, J., Pan, Y., McHardy, A. C., Schulze-Lefert, P.: Structure and functions of the bacterial root microbiota in wild and domesticated barley. Cell Host & Microbe 17, 392-404 (2015).
(abstract)

Zamioudis, C., Korteland, J., Van Pelt, J.A., van Hamersveld, M., Dombrowski, N., Bai, Y., Hanson; J., Van Verk, M.C., Ling, H.-Q., Schulze-Lefert, P., and Pieterse, C.M.J. Rhizobacterial volatiles and photosynthesis-related signals coordinate MYB72 in Arabidopsis roots during onset of induced systemic resistance and iron deficiency responses. The Plant Journal, 10.1111/tpj.12995 (2015).
abstract

2014

Dörmann, P., Kim, H., Ott, T., Schulze-Lefert, P., Trujillo, M., Wewer, V. and Hückelhoven, R. (2014) Cell-autonomous defense, re-organization and trafficking of membranes in plant-microbe interactions. New Phytologist 204, 815–822 first published online: 28 AUG 2014, DOI: 10.1111/nph.12978.
abstract

Guttman, D., McHardy, A.C. and Schulze-Lefert, P. (2014) Microbial genome-enabled insights into plant-microbe interactions. Nature Reviews Genetics 15, 797–813 (epublished ahead of print 30 September 2014, doi: 10.1038/nrg3748).
abstract

Ichikawa, M., Hirano, T., Enami, K., Fuselier, T., Kato, N., Kwon, C., Voigt, B., Schulze-Lefert, P., Baluška, F. and Sato, M.H. (2014), Syntaxin of plant proteins SYP123 and SYP132 mediate root hair tip growth in Arabidopsis thaliana, Plant Cell Physiol., 55(4): 790-800, doi: 10.1093/pcp/pcu048.
abstract

Kim, H., O‘Connell, R., Maekawa-Yoshikawa, M., Uemura, T., Neumann, U., Schulze-Lefert, P. (2014) The powdery mildew resistance protein RPW8.2 is carried on VAMP721/722 vesicles to the extrahaustorial membrane of haustorial complexes, The Plant Journal, 79, 835-847 (2014), doi: 10.1111/tpj.
abstract

Schlaeppi, K., Dombrowski, N., Garrido Oter, R., Ver Loren van Themaat, E., & Schulze-Lefert, P. (2014). Quantitative divergence of the bacterial root microbiota in Arabidopsis thaliana relatives. Proceedings of the National Academy of Sciences of the United States of America, 111(2), 585-592, doi:10.1073/pnas.132159711.
abstract

Weßling, R., Epple, P. M., Altmann, S., He, Y., Yang, L., Henz, S. R., McDonald, N., Wiley, K., Bader, K. C., Gläßer, C., Shahid Mukhtar, M., Haigis, S., Ghamsari, L., Stephens, A. E., Ecker, J. R., Vidal, M., Jones, J. D. G., Mayer, K. F. X., Ver Loren van Themaat, E., Weigel, D., Schulze-Lefert, P., Dangl, J. L., Panstruga, R. and Braun, P., (2014) Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life. Cell Host & Microbe, 6(3): 364-375.
abstract

2013

Acevedo-Garcia, J., Collins, N.C., Ahmadinejad, A., Ma, L., Houben, A., Bednarek, P., Benjdia, M., Altmüller, J., Nürnberg, P., Reinhardt, R., Schulze-Lefert, P. and Panstruga, R. (2013) Fine mapping and chromosome walking towards the Ror1 locus in barley (Hordeum vulgare L.). Theoretical and Applied Genetics 126(12), 2969-2982.
abstract

Bulgarelli, D., Schlaeppi, K., Spaepen, S., Ver Loren van Themaat, E. and Schulze-Lefert, P. (2013) Structure and functions of the bacterial microbiota of plants, Annual Review of Plant Biology Vol. 64, 807-838.
abstract

Chang, C., Yu, D., Jiao, J., Jing, S., Schulze-Lefert, P. and Shen, Q.-H. (2013) Barley MLA Immune Receptors Directly Interfere with Antagonistically Acting Transcription Factors to Initiate Disease Resistance Signaling, The Plant Cell 25, 1158-1173. First Published on March 26, 2013; doi:10.1105/tpc.113.109942
abstract

Hacquard, S., Kracher, B., Maekawa, T., Vernaldi, S., Schulze-Lefert, P.*, Ver Loren van Themaat, E.* (2013) Mosaic genome structure of the barley powdery mildew pathogen and conservation of transcriptional programs in divergent hosts, PNAS 110 (24) E2219-E2228, doi: 10.1073/pnas.1306807110.
*co-corresponding authors
abstract

This work was featured in: Nature Reviews Microbiology 11, 744 (2013) doi:10.1038/nrmicro3144, by Thomas D. Otto and Adam J. Reid: Cereal killers

Kopischke, M., Westphal, L., Schneeberger, K., Clark, R., Ossowski, S., Wewer, V., Fuchs, R., Landtag, J., Hause, G., Dörmann, P., Lipka, V., Weigel, D., Schulze-Lefert, P., Scheel, D. and Rosahl, S. (2013) Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans. The Plant Journal, 73, 456–468 (12 DEC 2012, DOI: 10.1111/tpj.12046).
abstract

Poraty-Gavra, L., Zimmermann, P., Haigis, S., Bednarek, P., Hazak, O., Rogovoy Stelmakh, O., Sadot, E., Schulze-Lefert, P., Gruissem, W. and Yalovsky, S. (2013) The Arabidopsis Rho GTPase AtROP6 functions in developmental and pathogen response pathways, Plant Physiology 161: 1172-1188, First Published on January 14, 2013, doi:10.1104/pp.112.213165.
abstract

Schlaeppi, K., Ver Loren van Themaat, E., Bulgarelli, D. and Schulze-Lefert, P. (2013) Arabidopsis thaliana as model for studies on the bacterial root microbiota. In: Molecular Microbial Ecology of the Rhizosphere: Vol. 1 & 2 (ed. F. J. de Bruijn), doi: 10.1002/9781118297674.ch23.
abstract

Wicker, T., Oberhaensli, S., Parlange, F., Buchmann, J.P., Shatalina, M., Roffler, S., Roi B.-D., Doležel, J., Šimková, H., Schulze-Lefert, P., Spanu, P.D., Bruggmann, R., Joelle Amselem, J., Quesneville, H., Ver Loren van Themaat, PE, Paape, T., Shimizu, K.K., and Keller, B. (2013) The wheat powdery mildew genome shows the unique evolution of an obligate biotroph. Nature Genetics 45, 1092-1096. abstract

Yun, H.S., Kwaaitaal, M., Kato, N., Yi, C., Park, S., Sato M.H., *Schulze-Lefert, P. and *Kwon, C. (2013) Requirement of vesicle-associated membrane protein 721 and 722 for sustained growth during immune responses in Arabidopsis. Mol. Cells Vol. 35, No. 6.
*co-corresponding authors
abtract

2012

Bai, S., Liu, J., Chang,Ch.,Zhang, L., Maekawa, T., Wang, Q., Xiao, W., Liu, Y., Chai, J., Takken, FLW., Schulze-Lefert, P., Shen, QH. Structure-Function Analysis of Barley NLR immune Receptor MLA10 Reveals Its Cell Compartment Specific Activity in Cell Death and Disease Resistance. PLoS Pathogens 8(6), e1002752 (2012).
abstract

Bulgarelli, D.*, Rott, M.*, Schlaeppi, K.*, Ver Loren van Themaat, E.*, Ahmadinejad, N., Assenza, F., Rauf, P., Huettel, P., Reinhardt, R., Schmelzer, E., Peplies, J., Gloeckner, F.-O., Amann, R., Eickhorst, T. and Schulze-Lefert, P. Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiota. Nature 488, 91-95 (2012).
* contributed equally.
abstract

This work was featured in: Hirsch, P. N., Mauchline, T.H.: Who is who in the plant root microbiome? Nature Biotechnology 30, 961-962 (2012).

Delgado-Cerezo, M., Sánchez-Rodríguez, C., Escudero, V., Virginia Fernández, P., Hernández-Blanco, C., Sánchez-Vallet, A., Jordá, L., Bednarek, P., Schulze-Lefert, P., Somerville, S., Estevez, J.M., Persson, S. and Molina, A.: Arabidopsis heterotrimeric G protein regulates cell wall-mediated resistance to necrotrophic fungi. Molecular Plant 5, 1 98-114 (2012).
abstract

Lebeis, S.L., Rott, M., Dangl, J.L.* and Schulze-Lefert, P.*: Culturing a plant microbiome at the cross-Rhodes, New Phytologist 196, 341–344 (2012). (abstract)

Maekawa, T., Kracher, B., Vernaldi, S., Ver Loren van Themaat, E. and Schulze-Lefert, P. (2012), Conservation of NLR-triggered immunity across plant lineages. PNAS 49, 20119-20123 (2012).
abstract

O’Connell*, R.J., Thon, M.R*. , Hacquard, S., Amyotte, SG, Kleemann, J., Torres, MF., Damm, U., Buiate, EA., Epstein, L., Alkan, N., Altmüller, J., Alvarado-Balderrama, L., Bauser, CL., Becker, C., Birren, BW., Chen, Z., Choi, J., Crouch, JA, Duvick, JP., Farman, ML, Gan, P., Heiman, D., Henrissat, B., Howard, RJ., Kabbage, M., Koch, C., Kracher, B., Kubo, Y., Law, AD., Lebrun, MH., Lee, Y-H., Miyara, I., Moore, N., Neumann, U., Nordström, K., Panaccione, DG., Panstruga, R., Place, M.,, Proctor, RH., Prusky, D., Rech, G., Reinhardt, R., Rollins, JA., Rounsley, S., Schardl, CL., Schwartz, DC., Shenoy, N., Shirasu, K., Sikhakolli, UR., Stüber, K., Sukno, SA., Sweigard, JA., Takano, Y., Takahara, H., Trail, F., van der Does, HC.,Voll, LM, Will, I., Young, S., Zeng, Q., Zhang, J., Zhou, S., Dickman, MB., Schulze-Lefert, P., Ver Loren van Themaat, E., Ma, LJ. and Vaillancourt, LJ. Life-style transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses, Nature Genetics, dx.doi.org/10.1038/ng.2372 (2012).
* contributed equally.
abstract

Serrano, M., Kanehara, K., Torres, M., Yamada, K., Tintor, N., Kombrink, E., Schulze-Lefert, P. and Saijo, Y. (2011) Repression of sucrose/ultraviolet-B light-induced flavonoid accumulation in microbe-associated molecular pattern-triggered immunity in Arabidopsis. Plant Physiol., 158, 408-422 (2012).
abstract

Uemura, T., Kim, H., Saito, C, Ebine, K., Ueda, T., Schulze-Lefert, P., and Nakano, A. Qa-SNAREs localised to the trans-Golgi network regulate multiple transport pathways and extracellular disease resistance in plants. PNAS 109, 1784-1789 (2012).
abstract

2011

Bednarek, P.,Piślewska-Bednarek, M., Ver Loren van Themaat, E., Maddula, R.K., Svatoš, A. and Schulze-Lefert, P. (2011) Conservation and clade-specific diversification of the pathogen-inducible tryptophan and indole glucosinolate metabolism in Arabidopsis thaliana relatives, New Phytologist 192, 713-726
abstract
This work was commented in:

New Phytologist (2011) 192: 566-569 by Nicole K. Clay: Chemical diversity on display in the plant innate immune systems of closely-related species

Hiruma, K., Nishiuchi, T., Kato, T., Bednarek, P., Okuno, T., Schulze-Lefert, P., and Takano, Y. (2011) Arabidopsis ENHANCED DISEASE RESISTANCE 1 is required for pathogen-induced expression of plant defensins in nonhost resistance and acts through interference of MYC2-mediated repressor function, Plant Journal 67, 980-92.
abstract

Maekawa; T., Cheng; W., Spiridon, LN., Töller; A. Lukasik; E., Saijo; Y., Liu, P.; Shen; Q. Micluta; MA., Somssich; IE., Takken; FL., Petrescu; A.-J., Chai, J. and Schulze-Lefert, P. (2011) Coiled-coil domain-dependent homodimerization of intracellular MLA immune receptors defines a minimal functional module for triggering cell death. Cell Host & Microbe 9, 187-199.
abstract

Maekawa, T., Kufer, T.A. and Schulze-Lefert, P. (2011), NLR functions in plant and animal immune systems - so far and yet so close, Nature Immunology 12, 818-826 (2011).
abstract

Schulze-Lefert, P. and Panstruga, R. (2011) A molecular concept connecting nonhost-resistance and pathogen speciation. In: Trends in Plant Science 16, 117-125.
abstract

2010

Bednarek, P., Kwon, C. and Schulze-Lefert, P. Not a peripheral issue: secretion in plant-microbe interactions, Current Opinion in Plant Biology 13, 378-387 (2010).
abstract

Bulgarelli, D; Biselli, C; Collins, N C; Consonni, G; Stanca, A M; Schulze-Lefert, P; Valè, G (2010): The CC-NB-LRR-Type Rdg2a Resistance Gene Confers Immunity to the Seed-Borne Barley Leaf Stripe Pathogen in the Absence of Hypersensitive Cell Death. In: PloS ONE, 5(9): e12599.
abstract

Christensen, A., Svensson, K., Thelin, L., Zhang, W., Tintor, N., Prins, D., Funke, N. Michalak, M., Schulze-Lefert, P., Saijo, Y., Sommarin, M., Widell, S. , Persson, S. (2010), Higher Plant Calreticulins Have Acquired Specialized Functions. In: PloS-one 5 (6): e 11342.
open access

Hiruma, K., Onozawa-Komori, M., Takahashi, F., Asakura, M., Bednarek, P., Okuno, T., Schulze-Lefert,P and Takanoa, Y. (2010), Entry Mode-Dependent Function of an Indole Glucosinolate Pathway in Arabidopsis for Nonhost Resistance against Anthracnose Pathogens, Plant Cell 22, 2429-2443.
abstract

Humphry, M; Bednarek, P; Kemmerling, B; Koh, S; Stein, M; Goebel, U; Stüber, K; Piślewska-Bednarek, M; Loraine, A; Schulze-Lefert, P; Somerville, S; Panstruga, R (2010): A regulon conserved in monocot and dicot plants defines a functional module in antifungal plant immunity. In: Proceedings of the National Academy of Sciences 107, 21896–21901.
abstract

Salomon, S; Grunewald, D; Stüber, K; Schaaf, S; MacLean, D; Schulze-Lefert, P*; Robatzek, S* (2010) : High throughput confocal imaging of intact live tissue enables quantification of membrane trafficking in Arabidopsis. Plant Physiology 154, 1096–1104.
*co-corresponding authors
abstract

Sanchez-Vallet, A., Ramos, B., Bednarek, P., Lopez, G., Piślewska-Bednarek, M., Schulze-Lefert, P. and Molina, A. (2010) Tryptophan-derived secondary metabolites in Arabidopsis thaliana confer nonhost resistance to necrotrophic Plectosphaerella cucumerina fungi, The Plant Journal, Plant Journal 63, 115-127.
abstract

Schulze-Lefert, P. (2010) Innate Immune responses in plants, Clinical Experimental Immunology 160: 62–69.
abstract

Seeholzer S., Tsuchimatsu T., Jordan, T., Bieri, S., Pajonk, S., Yang, W., Jahoor, A., Shimizu, K.K., Keller, B. and Schulze-Lefert, P. (2010): Diversity at the Mla powdery mildew resistance locus from cultivated barley reveals sites of positive selection. In: Molecular Plant-Microbe Interactions, 23, 497-509.
abstract

Serrano, M., Hubert, D.A., Dangl, J.L., Schulze-Lefert, P. and Kombrink, E. (2010): A chemical screen for suppressors of the avrRpm1-RPM1-dependent hypersensitive cell death response in Arabidopsis thaliana. Planta, 231, 1013-1023.
abstract

Spanu, P D; Abbott, JC; Amselem, J; Burgis, TA; Soanes, DM; Stüber, K; Ver Loren van Themaat, E; Brown, J K M; Butcher, SA; Gurr, SJ; Lebrun, M-H; Ridout, CJ; Schulze-Lefert, P; Talbot, N J; Ahmadinejad, N; Ametz, C; Barton, GR; Benjdia, M; Bidzinski, P; Bindschedler, LV; Both, M; Brewer, MT; Cadle-Davidson, L; Cadle-Davidson, MM; Collemare, J; Cramer, R; Francisco, L-R; Frenkel, O; Godfrey, D; Harriman, J; Hoede, C; King, B C; Klages, S; Kleemann, J; Knoll, D; Koti, PS; Kreplak, J; Lu, X; Maekawa, T; Mahanil, S; Milgroom, MG; Montana, G; Noir, S; O’Connell, RJ; Oberhaensli, S; Parlange, F; Pedersen, C; Quesneville, H; Reinhardt, R; Rott, M; Sacristán, S; Schmidt, SM; Schön, M; Skamnioti, P; Sommer, H; Stephens, A; Takahara, H; Thordal-Christensen, H; Vigouroux, M; Weßling, R; Wicker, T; Panstruga, R (2010): Genome expansion and gene loss in powdery mildew fungi reveal functional tradeoffs in extreme parasitism. In: Science 330, 1543-1546.
abstract

2009

Bednarek, P, Pislewska-Bednarek, M., Svatos, A., Schneider, B., Doubsky, J., Mansourova, M., Humphry, M., Consonni, C., Panstruga, R., Sanchez-Vallet, A., Molina, A., and Schulze-Lefert, P. (2009): A glucosinolate metabolism pathway imediates broadspectrum antifungal defense in plants. Science 323, 101-106; e-published ahead of print December 2008.
abstract
This work was featured in:

ACS Chem. Biol. 4 (2), 80-84. DOI: 10.1021/cb9000266, pp 82 - 83
Bednarek, Pawel and P. Schulze-Lefert: Role of Plant Secondary Metabolites at the host-pathogen Interface (2009). In: Annual Plant Reviews, 34, Chapter 8, 220 - 260

Bisseling, T., Dangl, J. and Schulze-Lefert, P. (2009), Next Generation Communication, Science Editorial, Science 324, p.691, 8 May 2009.
abstract

Lu, X., Tintor, N., Mentzel, T., Kombrink, E., Boller, T., Robatzek, S., Schulze-Lefert, P.* and Saijo, Y*. (2009), Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis ER glucosidase II allele, PNAS, 106, 22522-22527.
*co-corresponding authors
abstract

Meyer, D., Pajonk S, Micali C, O’Connell R, Schulze-Lefert P. (2009) Extracellular transport and integration of plant secretory proteins into pathogen-induced cell wall compartments. Plant Journal 57: 986-999.
abstract

Panstruga, R., Parker, J. and Schulze Lefert, P. (2009): SnapShot: Plant Immune Response Pathways. Cell 136, 978.e1.

Saijo, Y, Tintor, N, Lu, X, Rauf, P., Pajerowska-Mukhtar, K., Häweker, H., Dong, X., Robatzek, S. and Schulze-Lefert, P. (2009), Receptor quality control in the endoplasmic reticulum for plant innate immunity. EMBO Journal, 28, 3439-3449.
abstract

2008

Kwon, C., P. Bednarek, and P. Schulze-Lefert (2008): Secretory Pathways in Plant Immune Responses, Plant Physiology 147, 1575-1583.
abstract

Kwon, C., C. Neu, S. Pajonk, H. S. Yun, U. Lipka, M. E. Humphry, S. Bau, M. Straus, H. Rampelt, F. El Kasmi, G. Jürgens, J. Parker, R. Panstruga, V. Lipka and P. Schulze-Lefert (2008): Co-option of a default secretory pathway for plant immune responses. Nature 451, 835-840.
abstract

Kwon, C., R. Panstruga and P. Schulze-Lefert (2008): Les liaisons dangereuses: Immunological synapse formation in animals and plants. Trends in Immunology 29:159-166
abstract

Pajonk, S., C. Kwon, N. Clemens, R. Panstruga and P. Schulze-Lefert (2008): Activity determinants and functional specialization of Arabidopsis pen1 syntaxin in innate immunity. In: Journal of Biologicial Chemistry 283: 26974-26984.
abstract

Saijo, Y. and Schulze-Lefert, P. (2008): Manipulation of the eukaryotic transcriptional machinery by bacterial pathogens. Cell Host & Microbe 4: 96-99.
abstract

Töller, A., L. Brownfield, C. Neu, D. Twell and P. Schulze-Lefert (2008): Dual function of Arabidopsis glucan synthase-like genes GSL8 and GSL10 in male gametophyte development and plant growth. Plant Journal, 54: 911-923.
abstract

Yun, H.S., Panstruga, R., Schulze-Lefert, P., and Kwon, C. (2008) Ready to fire: Secretion in Plant Immunity. Plant Signaling and Behavior, 3: 505-508.
abstract

2007

Collins N.C., Niks R.E., and Schulze-Lefert P. (2007) Resistance to cereal rusts at the plant cell wall – what can we learn from other host-pathogen systems? Australian Journal of Agricultural Research 58: 476-489.
abstract

Miklis, M., C. Consonni, R. A. Bhat, V. Lipka, P. Schulze-Lefert and R. Panstruga (2007): Barley MLO Modulates Actin-Dependent and Actin-Independent Antifungal Defense Pathways at the Cell Periphery. Plant Physiology. 144: 1132-1143.
open access article

Serrano M, Robatzek S, Torres M, Kombrink E, Somssich IE, Robinson M, Schulze-Lefert P. (2007) Chemical interference of PAMP-triggered immune responses in Arabidopsis reveals a potential role for FAS II complex-derived lipid signals. J Biol Chem. 282: 6803 - 6811.
abstract

Shen, Q.-H., Saijo Y., Mauch S., Biskup C., Bieri S, Keller B, Seki H., lker B., Somssich I.E., and Schulze-Lefert P. (2007): Nuclear Activity of MLA Immune Receptors Links Isolate-Specific and Basal Disease-Resistance Responses. Science 315: 1098-1103.
abstract (full text)
This work was featured in:

Cell 128: 823-824, 2007. Jen Sheen and Ping He: Nuclear Actions in Innate Immune Signaling
Science 315: 1088-1089, 2007. Jeff L. Dangl: Nibbling at the Plant Cell Nucleus

Shen, Q.-H., and Schulze-Lefert, P. (2007): Rumble in the nuclear Jungle: compartmentalization, trafficking, and nuclear action of plant immune receptors. EMBO Journal 26: 4239-4301.
abstract

2006

Batchu A.K., Zimmermann D., Schulze-Lefert P., and Koprek T. (2006) Correlation between hordatine accumulation, environmental factors and genetic diversity in wild barley (Hordeum spontaneum C. Koch) accessions from the Near East Fertile Crescent. Genetica 127:87 99.
abstract

Chen Z., Hartmann H.A:, Wu M.-J., Friedman E.J., Chen J.-G., Pulley M., Schulze-Lefert P., Panstruga R., and Jones A.M. (2006) Expression analysis of the AtMlo gene family encoding plant-specific seven-transmembrane proteins. Plant Molecular Biology 60:583 597.
abstract

Consonni C., Humphry M.E., Hartmann H.A., Livaja M., Durner J., Westphal L., Vogel J., Lipka V., Kemmerling B., Schulze-Lefert P., Somerville S.C., and Panstruga R. (2006) Conserved requirement for a plant host cell protein in powdery mildew pathogenesis. Nature Genetics 38: 716-720.
abstract

Schulze-Lefert, P. and Robatzek, S. (2006) Plant Pathogens trick guard cells into opening the gates. Cell 126: 831-834.
abstract

Shimada, C., Lipka, V., O'Connell, R., Okuno, T., Schulze-Lefert, P., Takano, Y. (2006) Non-host resistance in Arabidopsis-Colletotrichum interactions acts at the cell periphery and requires actin filament function. MPMI 19: 270-279.
abstract

Stein, M., Dittgen J., S nchez-Rodriguez C., Hou B-H, Molina A., Schulze-Lefert P., Lipka V., and Somerville S. (2006) Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration. Plant Cell, 18(3): 731-746.
abstract
This work was featured in:
The Plant Cell 18: 523-528, 2006, Ellis J.: Insights into nonhost disease resistance: Can they assist disease control in agriculture?

Swarbrick P.J., Schulze-Lefert P., and Scholes J.D. (2006) Metabolic consequences of susceptibility and resistance (race-specific or broad spectrum) in barley leaves challenged with powdery mildew. Plant Cell and Environment 29: 1061-1076.
abstract

Zhao, T., Palotta, M., Langridge, P., Prasad, M., Graner, A., Schulze-Lefert, P., and Koprek, T. (2006) Mapped Ds/T-DNA launch pads for functional genomics in barley. Plant Journal 47: 811-826.
( abstract (full text)

2005

Bhat R.A., Miklis M., Schmelzer E., Schulze-Lefert P., and Panstruga R. (2005) Recruitment and interaction dynamics of plant penetration resistance components in a plasma membrane micro-domain. PNAS 102: 3135-3140.
abstract

Elliott C., M ller J., Miklis M., Bhat R.A., Schulze-Lefert P., and Pantruga R. (2005) Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO protein. Biochemical Journal 385: 243-254.
abstract

Farmer E., and Schulze-Lefert P. (2005) Biotic interactions. From molecular networks to inter-organismal communities. Current Opinion in Plant Biology 8: 343-345.

Freialdenhoven A., Orme J., Lahaye T., and Schulze-Lefert P. (2005) Barley Rom1 reveals a potential link between race-specific and nonhost resistance responses to powdery mildew fungi. MPMI 18: 291-299.
abstract

Lipka, V., Dittgen J., Bednarek P., Bhat R., Wiermer M., Stein M., Lantag J., Brandt W., Rosahl S., Scheel D., Llorente F., Molina A., Parker J., Somervillle S., Schulze-Lefert P. (2005) Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis. Science 310: 1180 1183.
abstract (full text)
This work was featured in:
The Plant Cell 18: 523-528, 2006, Ellis J.: Insights into nonhost disease resistance: Can they assist disease control in agriculture?

Muller J., Piffanelli P., Devoto A., Miklis M., Elliott C., Ortmann B., Schulze-Lefert P., and Panstruga P. (2005) Conserved ERAD-like quality control of a plant polytopic membrane protein. Plant Cell 17: 149-163.
abstract

Schulze-Lefert P. and Bieri S.(2005) Recognition at a Distance. Science 308: 506-508.
abstract (full text)

2004

Bieri S, Mauch S, Shen Q-H, Peart J, Devoto A, Casais C, Ceron F, Schulze S, Steinbi H.-H., Shirasu K, and Schulze-Lefert P (2004) RAR1 positively controls steady state levels of barley MLA resistance proteins and enables sufficient MLA6 accumulation for effective resistance. The Plant Cell 16, 3480-3495.
abstract

Piffanelli P., Ramsay L., Waugh R., Benabdelmouna A, D'Hont A., Hollricher K., Jorgensen J.H., Schulze-Lefert P., and Panstruga R. (2004) A barley cultivation-associated polymorphism conveys resistance to powdery mildew. Nature 430: 887-891.
abstract

Schulze-Lefert P. (2004) Knocking on the heaven's wall: pathogenesis of and resistance to biotrophic fungi at the cell wall. Current Opinion in Plant Biology 7: 377-383.
abstract

Schulze-Lefert P. (2004) Plant immunity: The origami of receptor activation. Current Biology 14: R22-R24.
abstract

Sadanandom A., Findlay K., Doonan J.H., Schulze-Lefert P., and Shirasu K. (2004) CHPA, a cysteine- and histidine-rich-domain-containing protein, contributes to maintenance of the diploid state in Aspergillus nidulans. Eukaryotic Cell 3: 984-991.
abstract

Zimmerli L., Stein M., Lipka V., Schulze-Lefert P., and Somerville S. (2004) Host and non-host pathogens elicit different jasmonate/ethylene responses in Arabidopsis. The Plant Journal 40: 633-646.
abstract

2003

Collins N.C., H. Thordal-Christensen, V. Lipka, S. Bau, E. Kombrink, J.-L. Qiu, R. H ckelhoven, M. Stein, A. Freialdenhoven, S.C. Somerville and P. Schulze-Lefert (2003): SNARE-protein-mediated disease resistance at the plant cell wall. Nature 425: 973-977.
abstract

Devoto A., Hartmann A., Piffanelli P., Elliott C., Simmons C., Taramino G., Goh C.-S., Cohen F.E., Emerson B.C., Schulze-Lefert P., and Panstruga P. (2003) Molecular phylogeny and evolution of the plant-specific seven transmembrane MLO family. J. Mol. Evolution 56: 77-88.
abstract

Jacobs A.K., V. Lipka, R.A. Burton, R. Panstruga, N. Strizhov, P. Schulze-Lefert and G.B. Fincher (2003) An Arabidopsis callose synthase, GSL5, is required for wound and papillary callose formation. The Plant Cell 15: 2503-2513.
abstract

Madsen L.H., Collins N.C., Rakwalska M., Backes G., Sandal N., Krusell L., Jensen J., Waterman E.H., Jahoor A., Ayliffe M., Pryor A.J., Langridge P., Schulze-Lefert P., and Stougaard, J. (2003) Barley disease resistance gene analogs of the NBS-LRR: identification and mapping. MGG 269: 150-161.
abstract

Panstruga R., Kim M.C., Cho M.J., and Schulze-Lefert P. (2003) Testing the efficiency of dsRNAi-constructs in vivo: A transient expression assay based on two fluorescent proteins. Molecular Biology Reports 30: 135-140.
abstract

Panstruga R., and Schulze-Lefert P. (2003) Corruption of host seven-transmembrane proteins by pathogenic microbes: a common theme in animals and plants?. Microbes and Infection 5: 429-437.
abstract

Schulze-Lefert P., and Panstruga R. (2003) Establishment of biotrophy by parasitic fungi and reprogramming of host cells for disease resistance. Annual Review of Phytopathology 41: 641-667.
abstract

Shen Q.-H., Zhou F., Bieri S., Haizel T., Shirasu K., and Schulze-Lefert P. (2003) Recognition specificity and RAR1/SGT1 dependence in barley Mla disease resistance genes to the powdery mildew fungus. Plant Cell 15: 732-744.
abstract

Shirasu K., and Schulze-Lefert P. (2003) Complex formation, promiscuity, and multi-functionality: protein interactions in disease resistance pathways. Trends in Plant Science 8: 252-258.
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2002

Azevedo C., Sadanandom A., Kitagawa K., Freialdenhoven A., Shirasu K., and Schulze-Lefert P. (2002) The RAR1 interactor SGT1, an essential component of R gene-triggered disease resistance. Science 295: 2073-2076.
abstract (full text)
This work was featured in:

Science 295: 2032-2033, 2002. Nishimura M., and Somerville S.: Resisting Attack.
Current Biology 12: R352-R354, 2002. W.A. Gray: Plant Defence: A New Weapon In The Arsenal.
Plant Cell Suppl. 2002: S5-S8. 2002. Dodds P.N., and Schwechheimer C.: A breakdown in defense signaling.

Collins N., Sadanandom A., and Schulze-Lefert P. (2002) Genes and molecular mechanisms controlling powdery mildew resistance in barley. In: The Powdery Mildews, A Comprehensive Treatise, B langer R.R., Bushnell W.R., Dik A.J., and Carver L.W., APS Press, St. Paul/Minnesota, pp. 134-145.

Elliott C., Zhou F., Spielmeyer W., Panstruga R., and Schulze-Lefert P. (2002) Functional conservation of wheat and rice Mlo orthologs in defense modulation to the powdery mildew fungus. MPMI 15: 1069-1077.
abstract

Kim M.C., Lee S.H., Kim J.K., Chun H.J., Ok H.M., Moon B.C., Kang C.H., Chung W.S., Park C.Y., Choi M.S., Kang Y.H., Koo S.C., Koo, Y.D., Jung J.C., Schulze-Lefert P., and Cho M.J. (2002) Mlo, a negative regulator of plant cell death, is a novel calmodulin-binding protein: isolation and characterization of Mlo homologue in rice. Journal Biol. Chem, 277: 19304-19314.
abstract

Kim M.C., Panstruga R., Elliott C., M ller J., Devoto A., Yoon H.W., Park H.C., Cho M.J., and Schulze-Lefert P. (2002) Calmodulin-regulated MLO defence suppression functions independently of heterotrimeric G proteins. Nature 416: 447-450.
abstract
This work was featured in:

TIPS 2002. Stein M., and Somerville S.C.: MLO, a novel modulator of plant defenses and cell death, binds calmodulin

Panstruga R., and Schulze-Lefert P. (2002) Live and let live: insights into powdery mildew disease and resistance. Molecular Plant Pathology 3: 495-502.
abstract

Piffanelli P., Zhou F., Casais C., Orme J., Schaffrath U., Collins N., Panstruga R., and Schulze-Lefert, P. (2002) The barley MLO modulator of defence and cell death is responsive to biotic and abiotic stimuli. Plant Physiol., 129: 1076-1085.
abstract
This work was featured in:

TIPS, 2002. Stein M., and Somerville S.C.: MLO, a novel modulator of plant defenses and cell death, binds calmodulin

Schulze-Lefert P., Shirasu K., Azevedo C., Piffanelli P., Eilliott C., Zhou F., Panstruga R., Kim M.-C., and Cho, M.-J. (2002) Molecular mechanisms in disease resistance to powdery mildew fungi. In: Biology of plant-microbe interactions Vol. 3, Leong S.A.., Allen C. and Triplett E.W. , Eds., Int. Society for Molecular Plant-Microbe Interactions, St. Paul/Minnesota, pp. 17-22.

2001

Collins N.C., Lahaye T., Peterh nsel C., Freialdenhoven A., Corbitt M., and Schulze-Lefert P. (2001) Sequence haplotypes revealed by sequence-tagged site fine mapping of the Ror1 gene in the centromeric region of barley chromosome 1H1[w]. Plant Physiology 125: 1236-1247.
abstract

Halterman D., Zhou F., Wei F., Wise R.P., and Schulze-Lefert P. (2001) The Mla6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria graminis f.sp. hordei in barley and wheat. Plant J. 25: 335-348.
abstract

Kurth J., Kolsch R., Simons V., and Schulze-Lefert P. (2001) A high-resolution genetic map and a diagnostic RFLP marker for the Mlg resistance locus to powdery mildew in barley. Theor. Appl. Genet. 102: 53-60.
abstract

Zhou F., Kurth J., Wei F., Elliott C., Val G., Yahiaoui N., Keller B., Somerville S., Wise R., and Schulze-Lefert P. (2001) Cell-autonomous expression of Barley Mla1 confers race-specific resistance to the powdery mildew fungus via a Rar1-independent signaling pathway. Plant Cell 13: 337-350.
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2000

Schulze-Lefert P., and Vogel J. (2000) Closing the ranks to attack by powdery mildew. Trends in Plant Science 5: 343-348.
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Schweizer P., Pokorny J., Schulze-Lefert P., and Dudler R. (2000) Double-stranded RNA interferes with gene function at the single-cell level in cereals. Plant J. 24: 895-903.
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Shirasu K., Schulman A.H., Lahaye T., and Schulze-Lefert P. (2000) A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion. Genome Res. 10: 908-915.
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Shirasu K., and Schulze-Lefert P. (2000) Regulators of cell death in disease resistance. Plant Mol. Biol. 44: 371-385.
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1999

Devoto A., Piffanelli, P., Nilsson, I., Wallin E., Panstruga R., von Heijne, G., and Schulze-Lefert, P. (1999) Topology, subcellular localization, and sequence diversity of the Mlo family in plants. J. Biol. Chem. 274: 34993-35004.
abstract

Leister D., Kurth J., Laurie D.A., Yano M., Sasaki T., Graner A., and Schulze-Lefert P. (1999) RFLP- and physical mapping of resistance gene homologues in rice (O.sativa) and barley (H.vulgare). Theor. Appl. Genet. 98: 509-520.
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Piffanelli P., Devoto A., and Schulze-Lefert P. (1999) Defence signalling pathways in cereals. Curr. Opinion Plant Biol. 2: 295-300.
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Shirasu K., Lahaye T., Tan M.-W., Zhou F., Azevedo C., and Schulze-Lefert P. (1999) A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Cell 99: 355-366.
abstract

Shirasu K., Nielsen K., Piffanelli P., Oliver R., and Schulze-Lefert P. (1999) Cell-autonomous complementation of mlo resistance using a biolistic transient expression system. Plant J. 17: 293-299.
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Wei F.S., Gobelman-Werner K., Morroll S.M., Kurth J., Mao L., Wing R., Leister D., Schulze-Lefert P., and Wise R. (1999) The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppressed recombination within a 240-kb DNA interval on chromosome 5S (1HS) of barley. Genetics 153: 1929-1948 abstract
and Genetics 154: 953-953. abstract

1998

Lahaye T., Hartmann S., Töpsch S., Freialdenhoven A., and Schulze-Lefert P. (1998) High-resolution genetic and physical mapping of the Rar1 locus in barley. Theor. Appl. Genet. 97: 526-534.
abstract

Lahaye T., Shirasu K., and Schulze-Lefert P. (1998) Chromosome landing at the barley Rar1 locus. Mol. Gen. Genet. 260: 92-101.

Leister D., Kurth J., Laurie D.A., Yano M., Sasaki T., Devos K., Graner A., and Schulze-Lefert P. (1998) Rapid reorganization of resistance gene homologues in cereal genomes. Proc. Natl. Acad. Sci. USA 95:370-375.
abstract

Panstruga R., Büschges R. Piffanelli P., and Schulze-Lefert P. (1998) A contiguous 60 kb genomic stretch from barley reveals molecular evidence for gene islands in a monocot genome. Nucleic Acids Research 26:1056-1062.
abstract

Spielmeyer M., Robertson M., Collins N., Leister D., Schulze-Lefert P., Seah S., Moullet O., and Lagudah E.S. (1998) A superfamily of disease resistance gene analogs is located on all homoeologous chromosome groups of wheat (Triticum aestivum). Genome 41: 782-788.
abstract

von Röpenack E., Parr A., and Schulze-Lefert P. (1998) Structural analyses and dynamics of soluble and cell wall bound phenolics in a broad spectrum resistance to the powdery mildew fungus in barley. J. Biol. Chem. 273: 9013-9022.
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1997

Büschges R., Hollricher K., Panstruga R., Simons G., Wolter M., Frijters A., van Daelen R., van der Lee T., Diergaarde P., Groenendijk J., Töpsch S., Vos P., Salamini F., and Schulze-Lefert P. (1997) The barley Mlo gene: A novel control element of plant pathogen resistance. Cell 88: 695-705.
abstract

Peterhänsel C., Freialdenhoven A., Kurth J., Kolsch R., and Schulze-Lefert P. (1997) Interaction analysis of genes required for resistance responses to powdery mildew in barley reveal distinct pathways leading to leaf cell death. Plant Cell 9: 1397-1409.
abstract

Schiffer R., Görg R., Jarosch B., Beckhove U., Bahrenberg G., Kogel, K.H., and Schulze-Lefert P. (1997) Tissue dependence and differential cordycepin sensitivity of race-specific resistance responses in the barley-powdery mildew interaction. Molecular Plant-Microbe Interactions 10: 830-839.
abstract

Schulze-Lefert P., Peterhänsel C., and Freialdenhoven A. (1997) Mutation analysis for the dissection of resistance. In: The Gene-for-Gene Relationship in Plant-Parasite Interactions, I.R. Crute, E.B. Holub and J.J. Burdon, Eds., UK: CAB International, pp. 45-63.

Simons G., van der Lee T., Diergaarde P., van Daelen R., Groenendijk J., Frijters A., Büschges R., Hollricher K., Töpsch S., Schulze-Lefert P., Salamini F., Zabeau F., and Vos P. (1997) AFLP-based fine mapping of the Mlo gene to a 30 kb DNA segment of the barley genome. Genomics 44: 61-70.
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1996

Freialdenhoven A., Peterhänsel C., Kurth J., Kreuzaler F., and Schulze-Lefert P. (1996) Identification of genes required for the function of non-race-specific mlo resistance to powdery mildew in barley. Plant Cell 8: 5-14.
abstract

Lahaye T., Rueger B., Toepsch S., Thalhammer J., and Schulze-Lefert P. (1996) Detection of single-copy sequences with digoxigenin-labeled probes in a complex plant genome after separation on pulsed-field gels. BioTechniques 21: 1067-1072.

1995

Schulze-Lefert P. (1995) Isolation of genes for resistance in plants. In: Novel approaches to integrated pest mangement, Reuveni R., Ed., CRC Press, Inc., USA, pp. 47-74.

Skadsen R.W., Schulze-Lefert P., and Herbst J.M. (1995) Molecular cloning, characterization and expression analysis of two catalase isozyme genes in barley. Plant Mol. Biol. 29: 1005-1014.
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1994

Freialdenhoven A., Scherag B., Hollricher K., Collinge D., Christensen H.T., and Schulze-Lefert P. (1994) Nar-1 and Nar-2, two loci required for Mla12-specified race-specific resistance to powdery mildew in barley. Plant Cell 6: 983-994.
abstract

Merkle T., Frohnmeyer H., Schulze-Lefert P., Dangl J.L., Hahlbrock K., and Schäfer E. (1994) Analysis of the parsley chalcone-synthase promoter in response to different light qualities. Planta 193: 275-282.
abstract

Schulze-Lefert P., Freialdenhoven A., Scherag B., and Görg R. (1994) Dissection of resistance pathways to powdery mildew attack. In: Advances in molecular genetics of plant-microbe interactions Vol. III, Daniels, M.J., Downie, J.A., Osbourn, A.E., Eds., Kluwer Academic Publishers Dordrecht/Boston/London, pp. 309-312.

1993

Görg R., Hollricher K., and Schulze-Lefert P. (1993) Functional analysis and RFLP-mediated mapping of the Mlg resistance gene in barley. Plant J. 3: 857-866.
abstract

Görg R., Hollricher K., and Schulze-Lefert P (1993) Functional analysis of the Mlg resistance locus in barley. In: Mechanisms of plant defense response Vol. II, Fritig B. and Legrand M., Eds., Kluwer Academic Publishers Dordrecht/Boston/London, pp. 45-48.

Wolter M., Hollricher K., Salamini F., and Schulze-Lefert P. (1993) The mlo resistance alleles in barley trigger a defense mimic phenotype. Mol. Gen. Genet. 239: 122-128.
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1991

Becker-Andre M., Schulze-Lefert P., and Hahlbrock K. (1991) Structural comparison, modes of expression, and putative cis-acting elements of the two 4-Coumarate: CoA Ligase genes in potato. J. Biol. Chem. 266: 8551-8559.
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Hauffe K.D., Neunzig U., Ites-Morales M.E., Ellard M., Schulze-Lefert P., Hahlbrock K., Dangl J.L., and Douglas C.J. (1991) A parsley 4CL-1 promoter fragment specifies complex expression patterns in transgenic tobacco. Plant Cell 3: 435-443.
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Hinze K., Thompson R.D., Ritter E., Salamini F., and Schulze-Lefert P. (1991) RFLP-mediated targeting of the mlo resistance locus in barley (Hordeum vulgare). Proc. Natl. Acad. Sci. USA 88: 3691-3695.
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Weißhaar B., Block A., Armstrong G.A., Herrmann A., Schulze-Lefert P., and Hahlbrock K. (1991) Regulatory elements required for light-mediated expression of the Petroselinum crispum chalcone synthase gene. In: Molecular Biology of Plant Development Vol. 45, Jenkins G.I., Schuch W., Eds., Cambridge UK, pp. 191-210.

1990

Block A., Dangl J.L., Hahlbrock K., and Schulze-Lefert P. (1990) Functional borders, genetic fine structure, and distance requirements of cis elements mediating light responsiveness of the parsley chalcone synthase promoter. Proc. Natl. Acad. Sci. USA 87: 5387-5391.
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1989

Schulze-Lefert P., Becker-Andre M., Schulz W., Hahlbrock K., and Dangl J.L. (1989) Functional architecture of the light-responsible chalcone synthase promoter from parsley. Plant Cell 1: 707-714.
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Schulze-Lefert P., Dangl J.L., Becker-Andre M., Hahlbrock K., and Schulz W. (1989) Inducible in vivo footprints define sequences necessary for UV-light activation of the parsley chalcone synthase gene. EMBO J. 8: 651-656.
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