Amanda Souza Camara: Modeling the dynamics of plant chromosomes

Beyond the genomic sequence, the peculiar three-dimensional structure of the DNA largely varies during the cell cycle and even between tissues or species. Its different conformations and organization inside the nucleus are now recognized to affect epigenetic regulation. It is becoming increasingly important to understand the mechanisms that drive the spatial organization of the genome. In this seminar, I will consider the DNAs physical properties to model the compaction of chromocenters and holocentric chromosomes.”