Korrespondierender Autor

Dr. Csaba Koncz
Telefon:+49 221 5062-230Fax:+49 221 5062-213

Developmental Biology • Plant Research

Research report (imported) 2012 - Max Planck Institute for Plant Breeding Research

Regulatory roles of plant TFIIH protein kinases


Koncz, Csaba


Abteilung Entwicklungsbiologie der Pflanzen

RNA polymerase II transcribes protein coding and several classes of regulatory RNAs in multicellular organisms. The C-terminal domain of the RNAPII largest subunit, RNAPII-CTD, carries conserved heptapeptide repeats that are phosphorylated at different residues by a protein kinase cascade in Arabidopsis. Recent studies start to reveal how phosphorylation of the RNAPII-CTD by TFIIH-associated protein kinases regulates growth and development via coordinated control of transcription, cell cycle and biogenesis of microRNAs and small silencing siRNAs.

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